Vascular smooth muscle cells (SMCs), a major structural component of the vessel wall, not
only play a key role in maintaining vascular structure but also perform various functions …

The vasculature plays an indispensible role in organ development and maintenance of
tissue homeostasis, such that disturbances to it impact greatly on developmental and …

Rationale: Pericytes are key regulators of vascular maturation, but their value for cardiac
repair remains unknown. Objective: We investigated the therapeutic activity and mechanistic …

Background—Clinical trials in ischemic patients showed the safety and benefit of autologous
bone marrow progenitor cell transplantation. Non–bone marrow progenitor cells with …

Background: Formation of new blood vessels, by either angiogenesis or vasculogenesis, is
critical for normal wound healing. Major processes in neovascularization include (i) growth …

We evaluated the healing potential of human fetal aorta-derived CD133+ progenitor cells
and their conditioned medium (CD133+ CCM) in a new model of ischemic diabetic ulcer …

Vascular, resident stem cells are present in all 3 layers of the vessel wall; they play a role in
vascular formation under physiological conditions and in remodeling in pathological …

Background. Mesenchymal stem cells (MSCs), also known as multipotent progenitor cells,
release several factors that support cell survival and enhance wound healing. We …

Millions of cardiomyocytes die immediately after myocardial infarction, regardless of whether
the culprit coronary artery undergoes prompt revascularization. Residual ischaemia in the …

Background Mesenchymal stromal cells may represent an ideal candidate to deliver anti-
cancer drugs. In a previous study, we demonstrated that exposure of mouse bone marrow …