TSST-1 promotes colonization of Staphylococcus aureus within the vaginal tract by activation of CD8+ T cells

K Dufresne, KF Al, HC Craig, CEM Coleman… - Infection and …, 2025 - journals.asm.org
Toxic shock syndrome toxin-1 (TSST-1) is a superantigen produced by Staphylococcus
aureus and is the determinant of menstrual toxic shock syndrome (mTSS); however, the …

Cell-Free Supernatant of Vaginal Viridans Streptococcus Induces Membrane Permeabilization and Transcriptional Regulation in Methicillin-Resistant Staphylococcus …

JAV Montecillo, HJ Yoo, YY Lee, C Park, A Cho… - Probiotics and …, 2024 - Springer
The genus Streptococcus is a heterogenous group of commensal and pathogenic bacteria
that are normal inhabitants of the human body, including the female genital tract (FGT). In …

Discovery of an antivirulence compound that targets the Staphylococcus aureus SaeRS two-component system to inhibit toxic shock syndrome toxin-1 production

K Dufresne, DA DiMaggio, CS Maduta… - Journal of Biological …, 2024 - jbc.org
Menstrual toxic shock syndrome (mTSS) is a rare but severe disorder associated with the
use of menstrual products such as high-absorbency tampons and is caused by …