Ischemia/reperfusion injury (IRI) is caused by a sudden temporary impairment of the blood
flow to the particular organ. IRI usually is associated with a robust inflammatory and …

The production of the pineal hormone melatonin is synchronized with day-night cycle via
multisynaptic pathway including suprachiasmatic nucleus linking several physiological …

Free radicals are involved in pathophysiology of ischemia/reperfusion injury (IRI). Melatonin
is a potent scavenger of reactive oxygen and nitrogen species. Thus, this study was …

The toxicity of aminoglycosides including gentamicin (GEN), the most widely used drug in
this category, is believed to be related to the generation of reactive oxygen species (ROS) in …

Free radicals, calcium overloading and loss of membrane phospholipids play an important
role in the development of ischemia/reperfusion (I/R) injury. Melatonin is a well-known …

Ischemic reperfusion kidney injury (IRKI) is a complex pathophysiological event, which is the
most common cause of the acute kidney injury. The key characteristic of IRKI is a reduction …

BACKGROUND: Reperfusion injury is a phenomenon that occurs when tissues are
subjected to ischaemia for a variable period of time, after which they are reperfused. Many …

Ischemia‐reperfusion (I‐R) injury is damage caused by restoring blood flow into ischemic
tissues or organs. This complex and characteristic lesion accelerates cell death induced by …

Purpose Traumatic brain injury (TBI) is a worldwide health problem with oxidative stress
recognized as a major pathogenetic factor. The present experimental study was designed to …

Background: Renal ischemia-reperfusion (I/R) injury is one of the major causes related to
acute kidney damage. Melatonin has been shown as a powerful antioxidant, with many …