Inflammatory mediators' essence in apical periodontitis

N Milojević, EK Lazic, L Lukic, D Puresevic… - European Oral …, 2024 - dergipark.org.tr
Apical periodontitis (AP) represents chronic inflammatory reaction of periradicular tissues of
teeth with necrotic pulp. Although AP has been considered as a multifactorial disease …

Nociceptor–Macrophage Interactions in Apical Periodontitis: How Biomolecules Link Inflammation with Pain

N Menon, A Kishen - Biomolecules, 2023 - mdpi.com
Periradicular tissues have a rich supply of peripheral afferent neurons, also known as
nociceptive neurons, originating from the trigeminal nerve. While their primary function is to …

Association between bacteria occurring in the apical canal system and expression of bone‐resorbing mediators and matrix metalloproteinases in apical periodontitis

A Takahama Jr, IN Rôças, ISP Faustino… - International …, 2018 - Wiley Online Library
Aim To evaluate the association between the presence of selected bacterial species/groups
in the apical root canal and expression of mediators of soft and bone tissue destruction in …

Expression of Toll-like receptors 2 and 4 and its association with matrix metalloproteinases in symptomatic and asymptomatic apical periodontitis

A Fernández, AM Cárdenas, J Astorga, P Veloso… - Clinical Oral …, 2019 - Springer
To determine Toll-like receptors (TLR) 2 and TLR4 expression levels and associate them
with matrix metalloproteinases (MMPs) in asymptomatic apical periodontitis (AAP) …

[HTML][HTML] Immunohistochemical expression of TGF-β1 and MMP-9 in periapical lesions

PR Álvares, JAA Arruda, LP Silva… - Brazilian oral …, 2017 - SciELO Brasil
The objective of this study was to evaluate the expression of matrix metalloproteinase 9
(MMP-9) and transforming growth factor beta (TGF-β1) in periapical lesion samples …

Osteoclast formation, inflammation, and matrix metalloproteinase-9 are downregulated in bone repair following root canal treatment in dogs teeth

FWG Paula-Silva, MFM Arnez… - Clinical oral …, 2021 - Springer
Objectives The aim of this study was to investigate the inflammatory infiltrate, osteoclast
formation, and expression of MMP-9 during the healing phase following root canal treatment …

Expression of matrix metalloproteinases and tissue inhibitor of matrix metalloproteinases during apical periodontitis development

CY Wan, L Li, LS Liu, CM Jiang, HZ Zhang… - Journal of Endodontics, 2021 - Elsevier
Abstract Introduction Matrix metalloproteinases (MMPs) and tissue inhibitors of matrix
metalloproteinases (TIMPs) are considered important mediators of the periapical immune …

Berberine regulates bone metabolism in apical periodontitis by remodelling the extracellular matrix

Y Cui, J Xie, L Cai, D Zhang, J Sun, X Zhou - Oral Diseases, 2023 - Wiley Online Library
Objectives The objectives of this study were to explore the role and related mechanism of
berberine in repairing bone destruction in apical periodontics (AP). Materials and Methods …

Baseline MMP expression in periapical granuloma and its relationship with periapical wound healing after surgical endodontic treatment

MA Ahmed, MF Anwar, K Ahmed, M Aftab, F Nazim… - BMC Oral Health, 2021 - Springer
Abstract Background Matrix metalloproteinases (MMPs) catalyzes the degradation of the
extracellular matrix components and have a major role in many physiological processes …

Role of matrix metalloproteinases and their tissue inhibitors in the pathological mechanisms underlying maxillofacial cystic lesions

K Kuźniarz, D Luchowska-Kocot… - Biomedical …, 2021 - spandidos-publications.com
Cystic lesions are considered to be one of the most common pathologies of the maxillofacial
region, and matrix metalloproteinases (MMPs) may represent potential etiological factors …