Two-photon and second harmonic microscopy in clinical and translational cancer research
SW Perry, RM Burke, EB Brown - Annals of biomedical engineering, 2012 - Springer
Application of two-photon microscopy (TPM) to translational and clinical cancer research
has burgeoned over the last several years, as several avenues of pre-clinical research have …
has burgeoned over the last several years, as several avenues of pre-clinical research have …
Confocal endomicroscopy: instrumentation and medical applications
JM Jabbour, MA Saldua, JN Bixler… - Annals of biomedical …, 2012 - Springer
Advances in fiber optic technology and miniaturized optics and mechanics have propelled
confocal endomicroscopy into the clinical realm. This high resolution, non-invasive imaging …
confocal endomicroscopy into the clinical realm. This high resolution, non-invasive imaging …
Shortwave infrared polymethine fluorophores matched to excitation lasers enable non-invasive, multicolour in vivo imaging in real time
ED Cosco, AL Spearman, S Ramakrishnan… - Nature …, 2020 - nature.com
High-resolution, multiplexed experiments are a staple in cellular imaging. Analogous
experiments in animals are challenging, however, due to substantial scattering and …
experiments in animals are challenging, however, due to substantial scattering and …
Neutrophils disturb pulmonary microcirculation in sepsis-induced acute lung injury
The lung is highly vulnerable during sepsis, yet its functional deterioration accompanied by
disturbances in the pulmonary microcirculation is poorly understood. This study aimed to …
disturbances in the pulmonary microcirculation is poorly understood. This study aimed to …
Exosome-based delivery of super-repressor IκBα relieves sepsis-associated organ damage and mortality
H Choi, Y Kim, A Mirzaaghasi, J Heo, YN Kim… - Science …, 2020 - science.org
As extracellular vesicles that play an active role in intercellular communication by
transferring cellular materials to recipient cells, exosomes offer great potential as a natural …
transferring cellular materials to recipient cells, exosomes offer great potential as a natural …
Endoscopic time-lapse imaging of immune cells in infarcted mouse hearts
Rationale: High-resolution imaging of the heart in vivo is challenging owing to the difficulty in
accessing the heart and the tissue motion caused by the heartbeat. Objective: Here, we …
accessing the heart and the tissue motion caused by the heartbeat. Objective: Here, we …
Staged development of long-lived T-cell receptor αβ TH17 resident memory T-cell population to Candida albicans after skin infection
Background Candida albicans is a dimorphic fungus to which human subjects are exposed
early in life, and by adulthood, it is part of the mycobiome of skin and other tissues. Neonatal …
early in life, and by adulthood, it is part of the mycobiome of skin and other tissues. Neonatal …
An extended NIR‐II superior imaging window from 1500 to 1900 nm for high‐resolution in vivo multiplexed imaging based on lanthanide nanocrystals
ZH Chen, X Wang, M Yang, J Ming, B Yun… - Angewandte …, 2023 - Wiley Online Library
High‐resolution in vivo optical multiplexing in second near‐infrared window (NIR‐II, 1000–
1700 nm) is vital to biomedical research. Presently, limited by bio‐tissue scattering, only …
1700 nm) is vital to biomedical research. Presently, limited by bio‐tissue scattering, only …
Rapid tumoritropic accumulation of systemically injected plateloid particles and their biodistribution
Nanoparticles for cancer therapy and imaging are designed to accumulate in the diseased
tissue by exploiting the Enhanced Permeability and Retention (EPR) effect. This limits their …
tissue by exploiting the Enhanced Permeability and Retention (EPR) effect. This limits their …
Optical fibers for high-resolution in vivo microendoscopic fluorescence imaging
Optical fiber-based high-resolution fluorescence imaging techniques have promising
applications in clinical practice and preclinical research using animals. Here we review the …
applications in clinical practice and preclinical research using animals. Here we review the …