The specificity protein (Sp) transcription factors (TFs) Sp1, Sp2, Sp3 and Sp4 exhibit
structural and functional similarities in cancer cells and extensive studies of Sp1 show that it …

Colorectal cancer (CRC) is the third most fatal and fourth most frequently diagnosed
neoplasm in the world. Numerous non-coding RNAs have been shown to contribute in the …

Breast cancer which is the most common type of diagnosed cancer among women
worldwide possesses metastatic potential, multi‑drug resistance, and high mortality. The NF …

Background Barium enema (BE) is widely available for diagnosis of colorectal cancer
despite concerns about its accuracy and acceptability. Computed tomographic …

Abstract Background Long noncoding RNAs (lncRNAs) have emerged as key regulators in
multiple cancers, including colorectal cancer (CRC). However, the biological functions and …

Ubiquitin-conjugating enzyme E2 J1 (UBE2J1) has been proven to participate in the
ubiquitination of multiple substrate proteins. However, the underlying mechanisms of …

Aim Previous studies have reported that circular RNA (circRNA) is associated with the
pathogenesis of CRC. This study was designed to reveal the mechanism of circ-ring finger …

Background Recent studies have investigated the role of circular RNAs (circRNAs) as
significant regulatory factors in multiple cancer progression. Nevertheless, the biological …

Background Hypoxic tumour microenvironment (TME) is a key regulator in cancer
progression. However, the communications between hypoxic cells and other components in …

Colorectal cancer (CRC) is the third most common type of cancer worldwide amongst males
and females. CRC treatment is multidisciplinary, often including surgery, chemotherapy, and …