Isolation and characterization of urinary extracellular vesicles: implications for biomarker discovery
ML Merchant, IM Rood, JKJ Deegens… - Nature Reviews …, 2017 - nature.com
Urine is a valuable diagnostic medium and, with the discovery of urinary extracellular
vesicles, is viewed as a dynamic bioactive fluid. Extracellular vesicles are lipid-enclosed …
vesicles, is viewed as a dynamic bioactive fluid. Extracellular vesicles are lipid-enclosed …
Proteomics, transcriptomics and lipidomics of exosomes and ectosomes
Mammalian cells secrete two types of extracellular vesicles either constitutively or in a
regulated manner: exosomes (50–100 nm in diameter) released from the intracellular …
regulated manner: exosomes (50–100 nm in diameter) released from the intracellular …
Toward tailored exosomes: the exosomal tetraspanin web contributes to target cell selection
S Rana, S Yue, D Stadel, M Zöller - … journal of biochemistry & cell biology, 2012 - Elsevier
Exosomes are discussed as potent therapeutics due to efficient transfer of proteins, mRNA
and miRNA in selective targets. However, therapeutic exosome application requires …
and miRNA in selective targets. However, therapeutic exosome application requires …
To protect and to preserve: novel preservation strategies for extracellular vesicles
Extracellular vesicles (EVs)-based therapeutics are based on the premise that EVs shed by
stem cells exert similar therapeutic effects and these have been proposed as an alternative …
stem cells exert similar therapeutic effects and these have been proposed as an alternative …
Extracellular vesicles and matrix remodeling enzymes: the emerging roles in extracellular matrix remodeling, progression of diseases and tissue repair
Extracellular vesicles (EVs) are membrane enclosed micro-and nano-sized vesicles that are
secreted from almost every species, ranging from prokaryotes to eukaryotes, and from …
secreted from almost every species, ranging from prokaryotes to eukaryotes, and from …
Preservation of small extracellular vesicles for functional analysis and therapeutic applications: a comparative evaluation of storage conditions
JY Wu, YJ Li, XB Hu, S Huang, DX Xiang - Drug Delivery, 2021 - Taylor & Francis
Extracellular vesicles (EVs) are nanovesicles involved in multiple biological functions. Small
EVs (sEVs) are emerging as therapeutics and drug delivery systems for their contents …
EVs (sEVs) are emerging as therapeutics and drug delivery systems for their contents …
ExoCarta as a resource for exosomal research
Exosomes are a class of extracellular vesicles that are secreted by various cell types. Unlike
other extracellular vesicles (ectosomes and apoptotic blebs), exosomes are of endocytic …
other extracellular vesicles (ectosomes and apoptotic blebs), exosomes are of endocytic …
Mass-spectrometry-based molecular characterization of extracellular vesicles: lipidomics and proteomics
This review discusses extracellular vesicles (EVs), which are submicron-scale, anuclear,
phospholipid bilayer membrane enclosed vesicles that contain lipids, metabolites, proteins …
phospholipid bilayer membrane enclosed vesicles that contain lipids, metabolites, proteins …
Proteomic techniques for characterisation of mesenchymal stem cell secretome
HK Skalnikova - Biochimie, 2013 - Elsevier
Mesenchymal stem cells (MSCs) are multipotent cells with a substantial potential in human
regenerative medicine due to their ability to migrate to sites of injury, capability to suppress …
regenerative medicine due to their ability to migrate to sites of injury, capability to suppress …
Cellular crosstalk regulates the aqueous humor outflow pathway and provides new targets for glaucoma therapies
Primary congenital glaucoma (PCG) is a severe disease characterized by developmental
defects in the trabecular meshwork (TM) and Schlemm's canal (SC), comprising the …
defects in the trabecular meshwork (TM) and Schlemm's canal (SC), comprising the …