The Hallmarks of Cervical Cancer: Molecular Mechanisms Induced by Human Papillomavirus

P Rosendo-Chalma, V Antonio-Véjar, JG Ortiz Tejedor… - Biology, 2024 - mdpi.com
Simple Summary The role of human papillomavirus (HPV) in cervical carcinogenesis is
widely documented; however, with an increasing number of scientific publications on the …

Human papillomavirus associated cervical lesion: pathogenesis and therapeutic interventions

J Ye, L Zheng, Y He, X Qi - MedComm, 2023 - Wiley Online Library
Human papillomavirus (HPV) is the most prevalent sexually transmitted virus globally.
Persistent high‐risk HPV infection can result in cervical precancerous lesions and cervical …

Evidence that cervical cancer cells cultured as tumorspheres maintain high CD73 expression and increase their protumor characteristics through TGF‐β production

R García‐Rocha, A Monroy‐García… - Cell Biochemistry …, 2022 - Wiley Online Library
Recently, a link between the biological activity of CD73 and tumorigenicity in solid tumors
has been proposed. We previously reported that the generation of adenosine (Ado) by the …

Epigenetic regulation of epithelial–mesenchymal transition during cancer development

S Yoodee, V Thongboonkerd - International Review of Cell and Molecular …, 2023 - Elsevier
Epithelial–mesenchymal transition (EMT) plays essential roles in promoting malignant
transformation of epithelial cells, leading to cancer progression and metastasis. During EMT …

[PDF][PDF] The roles of NOP56 in cancer and SCA36

S Zhao, D Zhang, S Liu, J Huang - Pathology and Oncology …, 2023 - por-journal.com
NOP56 is an essential nucleolar protein with a molecular mass of 66 KDa. NOP56 and
NOP58 are highly homologous throughout the sequence, with a KKE/D repeat at the …

A three‐dimensional microenvironment alters CD73 expression in cervical cancer

IC Iser, P de Andrade Mello, S Davies… - Cell Biochemistry …, 2021 - Wiley Online Library
Stem‐like cells (CSCs) have a tumour‐initiating capacity and play critical role in tumour
metastasis, relapse and resistance to therapy. The ectoenzyme CD73, encoded by the NT5E …

Type 2 human papillomavirus E7 attenuates E-cadherin expression in human keratinocytes

JY Song, YM Park, SY Choi - Journal of Microbiology, 2021 - Springer
Human papillomaviruses (HPVs) are known to utilize the down-regulation of epithelial (E)-
cadherin, a major component of adherens junctions of keratinocytes, to evade host immune …

The Hallmarks of Cervical Cancer: Molecular Mechanisms Induced by Human Papillomavirus

JI Ortiz Segarra, BJ Vega Crespo, GD Bigoni Ordonez - 2024 - dspace.ucuenca.edu.ec
Human papillomaviruses (HPVs) and, specifically, high-risk HPVs (HR-HPVs) are identified
as necessary factors in the development of cancer of the lower genital tract, with CaCU …

Association between gene expression and promoter methylation of CGB3, GSTP1 and NOP56 genes and their potential in biomarker development-associated …

P Singh - 2021 - digital.car.chula.ac.th
Binding of DNMT1-E7 complex can induce promoter methylation in tumor suppressor genes,
such as CCNA1, CADM1 leading to their expression suppression and thus, cause cancer …