Updated international consensus report on the investigation and management of primary immune thrombocytopenia

D Provan, DM Arnold, JB Bussel, BH Chong… - Blood …, 2019 - ashpublications.org
Over the last decade, there have been numerous developments and changes in treatment
practices for the management of patients with immune thrombocytopenia (ITP). This article is …

Immune thrombocytopenia

N Cooper, W Ghanima - New England Journal of Medicine, 2019 - Mass Medical Soc
Key Clinical Points Immune Thrombocytopenia Immune thrombocytopenia (ITP) is
diagnosed in patients with a platelet count below 100,000 per cubic millimeter in whom …

Rilzabrutinib, an oral BTK inhibitor, in immune thrombocytopenia

DJ Kuter, M Efraim, J Mayer, M Trněný… - … England Journal of …, 2022 - Mass Medical Soc
Background Rilzabrutinib, an oral, reversible covalent inhibitor of Bruton's tyrosine kinase,
may increase platelet counts in patients with immune thrombocytopenia by means of dual …

How we treat primary immune thrombocytopenia in adults

X Liu, Y Hou, M Hou - Journal of Hematology & Oncology, 2023 - Springer
Primary immune thrombocytopenia (ITP) is an immune-mediated bleeding disorder
characterized by decreased platelet counts and an increased risk of bleeding. Multiple …

Cancer and platelet crosstalk: opportunities and challenges for aspirin and other antiplatelet agents

XR Xu, GM Yousef, H Ni - Blood, The Journal of the American …, 2018 - ashpublications.org
Platelets have long been recognized as key players in hemostasis and thrombosis;
however, growing evidence suggests that they are also significantly involved in cancer, the …

[HTML][HTML] Severe bleeding events in adults and children with primary immune thrombocytopenia: a systematic review

C Neunert, N Noroozi, G Norman, GR Buchanan… - Journal of Thrombosis …, 2015 - Elsevier
Background The burden of severe bleeding in adults and children with immune
thrombocytopenia (ITP) has not been established. Objectives To describe the frequency and …

Phase 2 study of efgartigimod, a novel FcRn antagonist, in adult patients with primary immune thrombocytopenia

AC Newland, B Sánchez‐González… - American journal of …, 2020 - Wiley Online Library
Primary immune thrombocytopenia (ITP) is an acquired autoimmune bleeding disorder,
characterized by a low platelet count (< 100× 109/L) in the absence of other causes …

High-dose dexamethasone vs prednisone for treatment of adult immune thrombocytopenia: a prospective multicenter randomized trial

Y Wei, X Ji, Y Wang, J Wang, E Yang… - Blood, The Journal …, 2016 - ashpublications.org
This study compared the efficacy and safety of high-dose dexamethasone (HD-DXM) and
conventional prednisone (PDN) on the largest cohort to date as first-line strategies for newly …

Immune thrombocytopenia-current diagnostics and therapy: recommendations of a joint working group of DGHO, ÖGHO, SGH, GPOH, and DGTI

A Matzdorff, O Meyer, H Ostermann, V Kiefel… - Oncology research and …, 2018 - karger.com
Immune thrombocytopenia (ITP) is a rare disorder and meets the criteria for an orphan
disease. Expertise in the management of these patients is not widely spread. The following …

Eltrombopag for the treatment of children with persistent and chronic immune thrombocytopenia (PETIT): a randomised, multicentre, placebo-controlled study

JB Bussel, PG de Miguel, JM Despotovic… - The Lancet …, 2015 - thelancet.com
Background The oral thrombopoietin receptor agonist eltrombopag is approved for treatment
of adults with chronic immune thrombocytopenia. In the PETIT trial, we aimed to investigate …