Peptide self-assembly: thermodynamics and kinetics
J Wang, K Liu, R Xing, X Yan - Chemical Society Reviews, 2016 - pubs.rsc.org
Self-assembling systems play a significant role in physiological functions and have therefore
attracted tremendous attention due to their great potential for applications in energy …
attracted tremendous attention due to their great potential for applications in energy …
Self-assembly of peptides: The acceleration by molecular dynamics simulations and machine learning
N Cao, K Huang, J Xie, H Wang, X Shi - Nano Today, 2024 - Elsevier
Peptides, biopolymeric compounds connected by peptide bonds, have garnered significant
attention in recent years as their potential wide applications in fields such as drug delivery …
attention in recent years as their potential wide applications in fields such as drug delivery …
[HTML][HTML] Self-assembling peptide biomaterials: Insights from spontaneous and enhanced sampling molecular dynamics simulations
BJ Williams-Noonan, A Kamboukos… - Chemical Physics …, 2023 - pubs.aip.org
Peptide self-assembly is the process by which peptide molecules aggregate into low
dimensional (1D, 2D) or 3D ordered materials with potential applications ranging from drug …
dimensional (1D, 2D) or 3D ordered materials with potential applications ranging from drug …
β-barrel oligomers as common intermediates of peptides self-assembling into cross-β aggregates
Oligomers populated during the early amyloid aggregation process are more toxic than
mature fibrils, but pinpointing the exact toxic species among highly dynamic and …
mature fibrils, but pinpointing the exact toxic species among highly dynamic and …
Expanding the nanoarchitectural diversity through aromatic di-and tri-peptide coassembly: Nanostructures and molecular mechanisms
Molecular self-assembly is pivotal for the formation of ordered nanostructures, yet the
structural diversity obtained by the use of a single type of building block is limited …
structural diversity obtained by the use of a single type of building block is limited …
Amyloid self‐assembly of hIAPP8‐20 via the accumulation of helical oligomers, α‐helix to β‐sheet transition, and formation of β‐barrel intermediates
The self‐assembly of human islet amyloid polypeptide (hIAPP) into β‐sheet‐rich nanofibrils
is associated with the pathogeny of type 2 diabetes. Soluble hIAPP is intrinsically disordered …
is associated with the pathogeny of type 2 diabetes. Soluble hIAPP is intrinsically disordered …
Amphiphilic surface chemistry of fullerenols is necessary for inhibiting the amyloid aggregation of alpha-synuclein NACore
Featuring small sizes, caged structures, low cytotoxicity and the capability to cross biological
barriers, fullerene hydroxy derivatives named fullerenols have been explored as …
barriers, fullerene hydroxy derivatives named fullerenols have been explored as …
[HTML][HTML] Nucleation of β-rich oligomers and β-barrels in the early aggregation of human islet amyloid polypeptide
The self-assembly of human islet amyloid polypeptide (hIAPP) into β-sheet rich amyloid
aggregates is associated with pancreatic β-cell death in type 2 diabetes (T2D). Prior …
aggregates is associated with pancreatic β-cell death in type 2 diabetes (T2D). Prior …
The inhibitory effect of hydroxylated carbon nanotubes on the aggregation of human islet amyloid polypeptide revealed by a combined computational and …
Y Mo, S Brahmachari, J Lei, S Gilead… - ACS chemical …, 2018 - ACS Publications
Fibrillar deposits formed by the aggregation of the human islet amyloid polypeptide (hIAPP)
are the major pathological hallmark of type 2 diabetes mellitus (T2DM). Inhibiting the …
are the major pathological hallmark of type 2 diabetes mellitus (T2DM). Inhibiting the …
Distinct oligomerization and fibrillization dynamics of amyloid core sequences of amyloid-beta and islet amyloid polypeptide
A direct observation of amyloid aggregation from isolated peptides to cross-β fibrils is crucial
for understanding the nucleation-dependence process, but the corresponding macroscopic …
for understanding the nucleation-dependence process, but the corresponding macroscopic …