In recent years, our scientific interest in spaceflight has grown exponentially and resulted in
a thriving area of research, with hundreds of astronauts spending months of their time in …

The microgravity environment experienced during spaceflight severely impaired immune
system, making astronauts vulnerable to various diseases that seriously threaten the health …

Research in low Earth orbit (LEO) has become more accessible. The 2020
Biomanufacturing in Space Symposium reviewed space-based regenerative medicine …

All terrestrial organisms have evolved and adapted to thrive under Earth's gravitational force.
Due to the increase of crewed space flights in recent years, it is vital to understand how the …

Spirulina is the most studied cyanobacterium species for both pharmacological applications
and the food industry. The aim of the present review is to summarize the potential benefits of …

Glioblastoma multiforme (GBM) is one of the most aggressive malignant brain tumors and
urgently requires the development of new therapeutic strategies. In this study, an innovative …

Piezo1 channels are highly mechanically-activated cation channels that can sense and
transduce the mechanical stimuli into physiological signals in different tissues including …

Microgravity-induced bone loss is currently a significant and unresolved health risk for space
travelers, as it raises the likelihood for irreversible changes that weaken skeletal integrity …

Bone homeostasis is a dynamic equilibrium between bone-forming osteoblasts and bone-
resorbing osteoclasts. This process is primarily controlled by the most abundant and …

In space, cells sustain strong modifications of their mechanical environment.
Mechanosensitive molecules at the cell membrane regulate mechanotransduction pathways …