Introduction It is currently admitted that adverse drug reactions (ADRs) account for a great
burden of disease. Of particular concern are ADR-induced hospital admissions, particularly …

Background High-quality anticoagulation management is required to keep these narrow
therapeutic index medications as effective and safe as possible. This article focuses on the …

Pulmonary embolism is the third most common cause of death from cardiovascular disease
after heart attack and stroke. Sequelae occurring after venous thromboembolism include …

Background The risk of stroke varies considerably across different groups of patients with
atrial fibrillation (AF). Antithrombotic prophylaxis for stroke is associated with an increased …

Background Near-patient testing has made self-monitoring of anticoagulation with warfarin
feasible, and several trials have suggested that such monitoring might be equal to or better …

Background Many systematic reviews exist on interventions to improve safe and effective
medicines use by consumers, but research is distributed across diseases, populations and …

Vitamin K antagonists (VKAs) have been the mainstay of anticoagulation therapy for more
than 50 years. VKAs are mainly used for the prevention of stroke in patients with atrial …

Background The introduction of point‐of‐care devices for the management of patients on
oral anticoagulation allows self‐testing by the patient at home. Patients who self‐test can …

Background Current guidelines recommend oral anticoagulation therapy for patients with
atrial fibrillation (AF) with one or more risk factors for stroke; however, anticoagulation control …

Patients and caregivers play a central role in health care safety in the hospital, ambulatory
care setting, and community. Despite this, interventions to promote patient engagement in …