Trained immunity is a functional state of the innate immune response and is characterized
by long-term epigenetic reprogramming of innate immune cells. This concept originated in …

Background Available data show that COVID-19 vaccines may be less effective in
immunocompromised populations, who are at increased risk of severe COVID-19 …

Patients with kidney failure are at increased risk of SARS-CoV-2 infection, making effective
vaccinations a critical need. It is not known how well mRNA vaccines induce B and plasma …

Diabetes, hypertension and cardiovascular disease have been listed as risk factors for
severe coronavirus disease 2019 (COVID-19) since the first report of the disease in January …

Abstract Background Coronavirus disease (COVID–19) has resulted in the death of more
than 3.5 million people worldwide. While COVID–19 mostly affects the lungs, different …

The COVID-19 pandemic has profound adverse effects on the population on dialysis.
Patients requiring dialysis are at an increased risk of SARS-CoV-2 infection and mortality …

Background Haemodialysis (HD) patients are exposed to a high risk due to the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. They are prone to acquiring …

The first emergency-use authorizations for COVID-19 vaccines were granted by the Food
and Drug Administration in December 2020, and clinical trials for the approval of more …

Over the course of the COVID-19 pandemic, numerous studies have aimed to address the
challenges faced by patients with kidney disease and their caregivers. These studies …

Background An urgent need exists to improve the suboptimal COVID-19 vaccine response
in kidney transplant recipients (KTRs). We aimed to compare three alternative strategies with …