Western diets and chronic diseases

TE Adolph, H Tilg - Nature medicine, 2024 - nature.com
Abstract 'Westernization', which incorporates industrial, cultural and dietary trends, has
paralleled the rise of noncommunicable diseases across the globe. Today, the Western-style …

A systematic framework for understanding the microbiome in human health and disease: from basic principles to clinical translation

Z Ma, T Zuo, N Frey, AY Rangrez - Signal Transduction and Targeted …, 2024 - nature.com
The human microbiome is a complex and dynamic system that plays important roles in
human health and disease. However, there remain limitations and theoretical gaps in our …

dbCAN3: automated carbohydrate-active enzyme and substrate annotation

J Zheng, Q Ge, Y Yan, X Zhang, L Huang… - Nucleic Acids …, 2023 - academic.oup.com
Carbohydrate active enzymes (CAZymes) are made by various organisms for complex
carbohydrate metabolism. Genome mining of CAZymes has become a routine data analysis …

Primary succession of Bifidobacteria drives pathogen resistance in neonatal microbiota assembly

Y Shao, C Garcia-Mauriño, S Clare, NJR Dawson… - Nature …, 2024 - nature.com
Human microbiota assembly commences at birth, seeded by both maternal and
environmental microorganisms. Ecological theory postulates that primary colonizers dictate …

[HTML][HTML] A distinct clade of Bifidobacterium longum in the gut of Bangladeshi children thrives during weaning

T Vatanen, QY Ang, L Siegwald, SA Sarker, CI Le Roy… - Cell, 2022 - cell.com
The gut microbiome has an important role in infant health and development. We
characterized the fecal microbiome and metabolome of 222 young children in Dhaka …

[HTML][HTML] Ultra-deep sequencing of Hadza hunter-gatherers recovers vanishing gut microbes

MM Carter, MR Olm, BD Merrill, D Dahan, S Tripathi… - Cell, 2023 - cell.com
The gut microbiome modulates immune and metabolic health. Human microbiome data are
biased toward industrialized populations, limiting our understanding of non-industrialized …

The gut microbiome and early-life growth in a population with high prevalence of stunting

RC Robertson, TJ Edens, L Carr, K Mutasa… - Nature …, 2023 - nature.com
Stunting affects one-in-five children globally and is associated with greater infectious
morbidity, mortality and neurodevelopmental deficits. Recent evidence suggests that the …

Clinical sequelae of gut microbiome development and disruption in hospitalized preterm infants

R Thänert, DJ Schwartz, EC Keen, C Hall-Moore… - Cell host & …, 2024 - cell.com
Aberrant preterm infant gut microbiota assembly predisposes to early-life disorders and
persistent health problems. Here, we characterize gut microbiome dynamics over the first 3 …

The intersection of undernutrition, microbiome, and child development in the first years of life

F Fontaine, S Turjeman, K Callens, O Koren - Nature Communications, 2023 - nature.com
Undernutrition affects about one out of five children worldwide. It is associated with impaired
growth, neurodevelopment deficits, and increased infectious morbidity and mortality …

Longitudinal quantification of Bifidobacterium longum subsp. infantis reveals late colonization in the infant gut independent of maternal milk HMO composition

D Ennis, S Shmorak, E Jantscher-Krenn… - Nature …, 2024 - nature.com
Breast milk contains human milk oligosaccharides (HMOs) that cannot be digested by
infants, yet nourish their developing gut microbiome. While Bifidobacterium are the best …