A review on recent advances for the synthesis of bioactive pyrazolinone and pyrazolidinedione derivatives

A Abd-Ella, S Metwally, Y El-Ossaily… - Current Chemistry …, 2022 - growingscience.com
Oxo derivatives of pyrazolines and pyrazolidines are important heterocyclic compounds due
to their unique biological activities and have been widely applied in pharmaceutical and …

Synthesis and anticancer potential of certain novel 2-oxo-N'-(2-oxoindolin-3-ylidene)-2H-chromene-3-carbohydrazides

HA Abdel-Aziz, T Elsaman, A Al-Dhfyan, MI Attia… - European Journal of …, 2013 - Elsevier
Abstract Treatment of ethyl 3-hydrazinyl-3-oxopropanoate (6) with indoline-2, 3-dione
derivatives 7a–g gave ethyl 3-oxo-3-(2-(2-oxoindolin-3-ylidene) hydrazinyl) propanoates 8a …

Convenient one-pot MCRs to trifluoromethylated spiropiperidine under catalyst-free conditions

L Zhou, F Yuan, Y Zhou, W Duan, M Zhang, H Deng… - Tetrahedron, 2018 - Elsevier
One-pot, four-component reactions of 1, 2-diphenylpyrazolidine-3, 5-dione, ethyl 4, 4, 4-
trifluoroacetoacetate, aromatic aldehyde and ammonium acetate afforded highly …

Ni (II) complex with bishydrazone ligand: synthesis, characterization, DNA binding studies and pro-apoptotic and pro-differentiation induction in human cancerous cell …

NR Filipović, S Bjelogrlić, TR Todorović… - RSC …, 2016 - pubs.rsc.org
A new Ni (II) complex,[Ni (L)(H2O)](1), with diethyl 3, 3′-(2, 2′-(1, 1′-(pyridine-2, 6-diyl)
bis (ethan-1-yl-1-ylidene)) bis (hydrazin-1-yl-2-ylidene)) bis (3-oxopropanoate) ligand (H2L) …

The Reaction of Ethyl 2-oxo-2H-chromene-3-carboxylate with Hydrazine Hydrate

HA Abdel-Aziz, T Elsaman, MI Attia, AM Alanazi - Molecules, 2013 - mdpi.com
Although salicylaldehyde azine (3) was reported in 1985 as the single product of the
reaction of ethyl 2-oxo-2 H-chromene-3-carboxylate (1) with hydrazine hydrate, we identified …

Investigating the Synthesis Methods of 3, 5-dione Pyrazolidine and 3, 5-dione 1-phenylpyrazolidine in the Presence and Absence of Ultrasound Bath and their …

F Nadipour, S Salahvarzi… - Current Bioactive …, 2024 - ingentaconnect.com
Background: Pyrazolidine 5, 3-dione derivatives have a wide range of biological and
pharmacological activities and play an important role in the sub-structures of various drugs …

A new approach for one-pot, green synthesis of new polycyclic indoles in aqueous solution

M Ameri, A Asghari, A Amoozadeh… - Chinese Chemical …, 2017 - Elsevier
Electro-oxidation of phenylamine derivatives (1a and 1b) have been studied in the presence
of pyrazolidine-3, 5-dione (3) as a nucleophile in phosphate buffer solution mixed with …

Design, synthesis and characterization of some new pyrazol-pyrimidine derivatives and evaluation of their biological activities

R Rani, T Venkatesh, N Satyanarayan… - Current Chemistry …, 2023 - growingscience.com
In this work, we have reported a synthesis of some novel pyrazol-pyrimidine derivatives (3a-
f) obtained by the reaction of substituted pyrazole aldehydes and barbituric acid derivatives …

Synthesis and Characterization of Novel and Promising 1,2,4,4‐Tetranitropyrazolidine‐3,5‐dione for High Energy Materials Application

R Koorella, R Nayudu, R Gugulothu - ChemistrySelect, 2020 - Wiley Online Library
Abstract Novel high energy material 1, 2, 4, 4‐tetranitropyrazolidine‐3, 5‐dione has been
synthesized from inexpensive and readily available starting material Diethyl malonate. The …

[HTML][HTML] Unexpected products from the reaction of different compounds with hydrazine hydrate or aryl thiosemicarbazides

I Chaaban, M El Sayeda, MA Mahran… - Journal of Saudi …, 2016 - Elsevier
Abstract The reaction of 2, 5-dihydroxyacetophenone I or 1-(1, 4-dihydroxynaphthalen-2-yl)
ethanone II with various 4-aryl thiosemicarbazides did not yield the expected 4-aryl-1-[1-(2 …