Applications and limitations of dendrimers in biomedicine

AA Chis, C Dobrea, C Morgovan, AM Arseniu, LL Rus… - Molecules, 2020 - mdpi.com
Biomedicine represents one of the main study areas for dendrimers, which have proven to
be valuable both in diagnostics and therapy, due to their capacity for improving solubility …

[HTML][HTML] Endocytosis: the nanoparticle and submicron nanocompounds gateway into the cell

D Manzanares, V Ceña - Pharmaceutics, 2020 - mdpi.com
Nanoparticles (NPs) and submicron particles are increasingly used as carriers for delivering
therapeutic compounds to cells. Their entry into the cell represents the initial step in this …

[HTML][HTML] Dendrimers in the context of nanomedicine

AP Dias, S da Silva Santos, JV da Silva… - International journal of …, 2020 - Elsevier
Dendrimers are globular structures, presenting an initiator core, repetitive layers starting
radially from the core and terminal groups on the surface, resembling tree architecture …

The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles

E Fröhlich - International journal of nanomedicine, 2012 - Taylor & Francis
Many types of nanoparticles (NPs) are tested for use in medical products, particularly in
imaging and gene and drug delivery. For these applications, cellular uptake is usually a …

Dendrimers in drug delivery and targeting: Drug-dendrimer interactions and toxicity issues

K Madaan, S Kumar, N Poonia, V Lather… - Journal of Pharmacy …, 2014 - journals.lww.com
Dendrimers are the emerging polymeric architectures that are known for their defined
structures, versatility in drug delivery and high functionality whose properties resemble with …

Endocytosis of nanomedicines

G Sahay, DY Alakhova, AV Kabanov - Journal of controlled release, 2010 - Elsevier
Novel nanomaterials are being developed to improve diagnosis and therapy of diseases
through effective delivery of drugs, biopharmaceutical molecules and imaging agents to …

Dendrimers designed for functions: from physical, photophysical, and supramolecular properties to applications in sensing, catalysis, molecular electronics, photonics …

D Astruc, E Boisselier, C Ornelas - Chemical reviews, 2010 - ACS Publications
Dendrimers Designed for Functions: From Physical, Photophysical, and Supramolecular
Properties to Applications in Sensing, Catalysis, Molecular Electronics, Photonics, and …

Nanoparticle toxicity by the gastrointestinal route: evidence and knowledge gaps

IL Bergin, FA Witzmann - International journal of biomedical …, 2013 - inderscienceonline.com
The increasing interest in nanoparticles for advanced technologies, consumer products, and
biomedical applications has led to great excitement about potential benefits but also …

[HTML][HTML] PAMAM dendrimer-cell membrane interactions

LJ Fox, RM Richardson, WH Briscoe - Advances in colloid and interface …, 2018 - Elsevier
PAMAM dendrimers have been conjectured for a wide range of biomedical applications due
to their tuneable physicochemical properties. However, their application has been hindered …

Pharmaceutical nanotechnology for oral delivery of anticancer drugs

L Mei, Z Zhang, L Zhao, L Huang, XL Yang… - Advanced drug delivery …, 2013 - Elsevier
Oral chemotherapy is an important topic in the 21st century medicine, which may radically
change the current regimen of chemotherapy and greatly improve the quality of life of the …