Cannabinoids—the active components of Cannabis sativa and their derivatives—exert
palliative effects in cancer patients by preventing nausea, vomiting and pain and by …

Intrapartum-related events are the third leading cause of childhood mortality worldwide and
result in one million neurodisabled survivors each year. Infants exposed to a perinatal insult …

Abnormally high spiking activity can damage neurons. Signaling systems to protect neurons
from the consequences of abnormal discharge activity have been postulated. We generated …

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Balanced control of neuronal activity is central in maintaining function and viability of
neuronal circuits. The endocannabinoid system tightly controls neuronal excitability. Here …

2-Arachidonoylglycerol (2-AG) is a unique molecular species of monoacylglycerol isolated
in 1995 from rat brain and canine gut as an endogenous ligand for the cannabinoid …

Background Alzheimer's disease (AD) brain shows an ongoing inflammatory condition and
non-steroidal anti-inflammatories diminish the risk of suffering the neurologic disease …

Organophosphate (OP)-induced brain damage is defined as progressive damage to the
brain, resulting from the cholinergic neuronal excitotoxicity and dysfunction induced by OP …

Endovanilloids are defined as endogenous ligands of the transient receptor potential
vanilloid type 1 (TRPV1) protein, a nonselective cation channel that belongs to the large …

To date, N-arachidonoylethanolamine (anandamide) and 2-arachidonoylglycerol are the
best studied endocannabinoids and are thought to act as retrograde messengers in the …