NB compounds are potent and efficacious FOXM1 inhibitors in high-grade serous ovarian cancer cells

C Liu, M Vorderbruggen, C Muñoz-Trujillo… - Journal of Ovarian …, 2024 - Springer
Genetic studies implicate the oncogenic transcription factor Forkhead Box M1 (FOXM1) as a
potential therapeutic target in high-grade serous ovarian cancer (HGSOC). We evaluated …

FOXM1 transcriptional regulation

M Li, X Gao, Y Su, S Shan, W Qian, Z Zhang… - Biology of the …, 2024 - Wiley Online Library
FOXM1 is a key transcriptional regulator involved in various biological processes in
mammals, including carbohydrate and lipid metabolism, aging, immune regulation …

Novel FOXM1 inhibitor STL001 sensitizes human cancers to a broad-spectrum of cancer therapies

S Raghuwanshi, X Zhang, Z Arbieva, I Khan… - Cell Death …, 2024 - nature.com
Forkhead box protein M1 (FOXM1) is often overexpressed in human cancers and strongly
associated with therapy resistance and less good patient survival. The chemotherapy …

Theoretical investigations on modeling blood flow through vessel for understanding effectiveness of magnetic nanocarrier drug delivery systems

RM Alzhrani, MF Aldawsari, JA Alamoudi - Frontiers in Medicine, 2024 - frontiersin.org
For cancer therapy, the focus is now on targeting the chemotherapy drugs to cancer cells
without damaging other normal cells. The new materials based on bio-compatible magnetic …

CD99 contributes to the EWS:: FLI1 transcriptome by specifically affecting FOXM1‐targets involved in the G2/M cell cycle phase, thus influencing the Ewing sarcoma …

M Pasello, MA Laginestra, MC Manara… - Journal of Cell …, 2024 - Wiley Online Library
Ewing sarcoma (EwS), a highly aggressive malignancy affecting children and young adults,
is primarily driven by a distinctive oncogenic fusion, the EWSR1‐ETS, whose activity is a key …

A novel peptide CP29L, selected from the phage displayed cyclic random heptapeptide library, demonstrates its potent inhibitory effects to liver cancer HCCLM3 cells …

X Hua, K Xiang, A Liang, M Chang, S Jia… - European Journal of …, 2025 - Elsevier
FOXM1 is the “Achilles' heel” of cancers and hence the potential therapeutic target for
anticancer drug discovery. In this work, we selected high affinity peptides against the protein …

[HTML][HTML] Lasalocid inhibits melanoma by down-regulating FOXM1 through PI3K/AKT and JNK/P38 MAPK pathways

Q Yuan, H Jiang, M Zhu, Y Chu, Y Zhang… - Journal of …, 2025 - pmc.ncbi.nlm.nih.gov
Melanoma poses a significant challenge to patients due to its aggressive nature and limited
treatment options. Recent studies have suggested that lasalocid, a feed additive ionophore …

Anticancer peptide MCP-1 induces ferroptosis in liver cancer HCCLM3 cells by targeting FOXM1/ALOXE3 signal pathway

F Zhu, Z Shang, S Jia, Y Jiang, M Chang… - International Journal of …, 2024 - Springer
FOXM1 is a crucial oncogenic transcription factor involved in almost all cancer hallmark
pathways across all cancer types. Our previous work had found that FOXM1 targeted …

RNF26 up-regulates PD-L1 to regulate the cancer immune response in ccRCC.

W REN, J LI, R ZENG, L ZHU - Biocell, 2024 - search.ebscohost.com
Background: Clear cell renal cell carcinoma (ccRCC) stands as the most prevalent form of
kidney cancer, accounting for a significant proportion of malignancies affecting the kidneys …

Novel FOXM1 inhibitor STL001 sensitizes human cancers to a broad-spectrum of cancer therapies

A Gartel, S Raghuwanshi, X Zhang, Z Arbieva, Z Wang… - 2023 - ncbi.nlm.nih.gov
[WITHDRAWN] Novel FOXM1 inhibitor STL001 sensitizes human cancers to a broad-spectrum
of cancer therapies - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI …