miRNAs in cancer (review of literature)

B Smolarz, A Durczyński, H Romanowicz… - International journal of …, 2022 - mdpi.com
MicroRNAs (miRNAs) are short, noncoding, single-stranded RNA molecules that regulate
gene expression at the post-transcriptional level by binding to mRNAs. miRNAs affect the …

Extracellular vesicles in colorectal cancer: from tumor growth and metastasis to biomarkers and nanomedications

L Kotelevets, E Chastre - Cancers, 2023 - mdpi.com
Simple Summary Almost all cell types produce extracellular vesicles that, according to their
size, subcellular origin and release pathways, are mainly categorized as exosomes …

[HTML][HTML] HIF-1α overexpression in mesenchymal stem cell-derived exosome-encapsulated arginine-glycine-aspartate (RGD) hydrogels boost therapeutic efficacy of …

Q Wang, L Zhang, Z Sun, B Chi, A Zou, L Mao… - Materials Today Bio, 2021 - Elsevier
Aims Naturally secreted extracellular vesicles (EVs) play important roles in stem-mediated
cardioprotection. This study aimed to investigate the cardioprotective function and …

Overview of MicroRNAs as diagnostic and prognostic biomarkers for high-incidence cancers in 2021

C Zhang, C Sun, Y Zhao, Q Wang, J Guo, B Ye… - International journal of …, 2022 - mdpi.com
MicroRNAs (miRNAs) are small non-coding RNAs (ncRNAs) about 22 nucleotides in size,
which play an important role in gene regulation and are involved in almost all major cellular …

Insights on the biomarker potential of exosomal non-coding RNAs in colorectal cancer: an in silico characterization of related exosomal lncRNA/circRNA–miRNA …

M Mezher, S Abdallah, O Ashekyan, AA Shoukari… - Cells, 2023 - mdpi.com
Colorectal cancer (CRC) is one of the most common cancer types, ranking third after lung
and breast cancers. As such, it demands special attention for better characterization, which …

[HTML][HTML] New advances in the research of clinical treatment and novel anticancer agents in tumor angiogenesis

X Li, J Zhou, X Wang, C Li, Z Ma, Q Wan… - Biomedicine & …, 2023 - Elsevier
In 1971, Folkman proposed that tumors could be limited to very small sizes by blocking
angiogenesis. Angiogenesis is the generation of new blood vessels from pre-existing …

[HTML][HTML] Extracellular vesicles: Emerging mediators of cell communication in gastrointestinal cancers exhibiting metabolic abnormalities

G Pourali, N Zafari, H Fiuji, J Batra, E Nazari… - Cytokine & Growth …, 2023 - Elsevier
There is a complex interaction between pro-tumoural and anti-tumoural networks in the
tumour microenvironment (TME). Throughout tumourigenesis, communication between …

The application of extracellular vesicles in colorectal cancer metastasis and drug resistance: recent advances and trends

L Xiong, Y Wei, Q Jia, J Chen, T Chen, J Yuan… - Journal of …, 2023 - Springer
Colorectal cancer (CRC) has high incidence and mortality rates and is one of the most
common cancers of the digestive tract worldwide. Metastasis and drug resistance are the …

MicroRNA-nanoparticles against cancer: Opportunities and challenges for personalized medicine

E Martino, N D'Onofrio, C Anastasio, M Abate… - … Therapy-Nucleic Acids, 2023 - cell.com
Micro-RNAs (miRNAs) control gene expression at the post-transcriptional level and are
widely involved in carcinogenesis, playing a role as both oncogenes and tumor …

Baseline expression of exosomal miR-92a-3p and miR-221-3p could predict the response to first-line chemotherapy and survival in metastatic colorectal cancer

A Gherman, L Balacescu, C Popa, C Cainap… - International Journal of …, 2023 - mdpi.com
The status of predictive biomarkers in metastatic colorectal cancer is currently
underdeveloped. Our study aimed to investigate the predictive value of six circulating …