Alzheimer's disease (AD) 1− 3 is the most common form of dementia (estimated∼ 50− 60%
of all cases), associated with loss of memory (in particular episodic memory), cognitive …

Recent discoveries in zinc biology provide a new platform for discussing the primary
physiological functions of mammalian metallothioneins (MTs) and their exquisite zinc …

Metallothioneins (MTs) are a class of ubiquitously occurring low molecular mass, cysteine-
and metal-rich proteins containing sulfur-based metal clusters formed with Zn (II), Cd (II), and …

Alzheimer's disease is increasingly recognized to be linked to the function and status of
metal ions, and recently, the amyloid hypothesis has been strongly intertwined with the …

Metallothioneins (MT) are a family of small cysteine rich proteins, which since their discovery
in 1957, have been implicated in a range of roles including toxic metal detoxification …

Background: Many publications have investigated the association between metal ions and
the risk of Alzheimer's disease (AD), but the results were ambiguous. Aims: The objective of …

ADAM (a disintegrin and metalloproteinase) is a family of widely expressed, transmembrane
and secreted proteins of approximately 750 amino acids in length with functions in cell …

Metallothioneins (MTs) are a ubiquitous class of small metal-binding proteins involved in
metal homeostasis and detoxification. While known for their high affinity for d10 metal ions …

Metallothioneins (MTs) are low-molecular-mass cysteine-rich proteins with the ability to bind
mono-and divalent metal ions with the electron configuration d 10 in form of metal-thiolate …

As life expectancy increases, the number of people affected by progressive and irreversible
dementia, Alzheimer's Disease (AD), is predicted to grow. No drug designs seem to be …