Hepatoprotective effects of natural drugs: Current trends, scope, relevance and future perspectives

S Datta, D Aggarwal, N Sehrawat, M Yadav, V Sharma… - Phytomedicine, 2023 - Elsevier
Background: The liver is a well-known player in the metabolism and removal of drugs. Drug
metabolizing enzymes in the liver detoxify drugs and xenobiotics, ultimately leading to the …

Enhanced Sampling in Molecular Dynamics Simulations: How Many MD Snapshots can be Needed to Reproduce the Biological Behavior?

CA Tavares, TMR Santos… - Mini Reviews in …, 2024 - ingentaconnect.com
Since its early days in the 19th century, medicinal chemistry has concentrated its efforts on
the treatment of diseases, using tools from areas such as chemistry, pharmacology, and …

[PDF][PDF] Computational Docking Study of the Phytochemical Constituent, Silybin (Silybum marianum) against SARS-CoV-2 Omicron Variant Spike Glycoprotein: An In …

P Bansal, V Sharma, A Panwar, R Kumar… - J Pure Appl …, 2023 - researchgate.net
SARS-CoV-2 is continually evolving with the emergence of new variants with increased viral
pathogenicity. The emergence of heavily mutated Omicron (B. 1.1. 529) with spike protein …

P13K/AKT/mTOR<? A3B2 thyc= 10?> Pathway-Based<? A3B2 thyc?> Novel Biomarkers for Breast Cancer

V Sharma, A Panwar, AK Sharma - Re: GEN Open, 2021 - liebertpub.com
Background: Breast cancer has been the most recurrent frequent cause of cancer-related
deaths in women in India and all around the world. The treatment options have been …

[PDF][PDF] PI3Kinase/AKT/mTOR Pathway in Breast Cancer; Pathogenesis and Prevention with mTOR Inhibitors

V Sharma - Proceedings of IVSRTLSB-2021, 2022 - academia.edu
The most recurrent and considered second most frequent cause of cancerrelated death in
women is the breast cancer worldwide. In breast cancer cases patients are usually …

[PDF][PDF] In-silico designing of an inhibitor against mTOR FRB domain: Therapeutic implications against breast cancer

Worldwide breast cancer causes significant fatalities in women. The effective therapeutic
solution for treating the disease is using new and probable antagonistic biologically …