Nuclear medicine is composed of two complementary areas, imaging and therapy. Positron
emission tomography (PET) and single-photon imaging, including single-photon emission …

The use of radionuclides in medicine is based largely on the discoveries of two critical
concepts, the “tracer principle” and the “magic bullet”. In 1913, George de Hevesy …

Abstract Purpose The lead-203 (203Pb)/lead-212 (212Pb) elementally identical
radionuclide pair has gained significant interest in the field of image-guided targeted alpha …

We present the first approach to controlled metal chelation of peptide backbones, where the
anchoring site is an aza-amino acid nitrogen and the directionality of chelation events is …

Currently, receptor based radiopharmaceuticals have received great attention in molecular
imaging and radiotherapy of cancer, and provide a unique tool for target-specific delivery of …

In our effort to create imaging probes targeting the growth hormone secretagogue receptor
(GHSR), we now report on the design and synthesis of fluorine and rhenium containing …

Abstract Functionalized pyridyl ditopic ligands 1, 2‐phenylene diisonicotinate (pdi)(L1) and
N, N′‐4‐pyridylcarboxamide‐4‐pyridylcarboxyl‐1, 2‐benzene (pcpcb)(L2) comprising …

Radiolabeled proteolytic degradation-resistant somatostatin analogues have been of long-
standing interest as cancer imaging and radiotherapy agents for targeting somatostatin …

INTRODUCTION: To probe the interplay between radiotracer stability and somatostatin
receptor affinity, Tyr3-octreotate and six variations of its peptide sequence, for which the Re …

A signature feature of Alzheimer's disease is the accumulation of plaques, composed of
fibrillar amyloid-β protein (Aβ), in the brain parenchyma. Structural models of Aβ fibrils reveal …