VR Kohout, CL Wardzala, JR Kramer - Advanced drug delivery reviews, 2022 - Elsevier
Mucin glycoproteins are the major component of mucus and coat epithelial cell surfaces forming the glycocalyx. The glycocalyx and mucus are involved in the transport of nutrients …
Glycan recognition by lectins mediates important biological events. This Tutorial Review aims to introduce lectin–ligand interactions and show how these molecular recognition …
RE Detwiler, JR Kramer - Current Opinion in Solid State and Materials …, 2022 - Elsevier
Mucus is an essential barrier material that separates organisms from the outside world. This slippery material regulates the transport of nutrients, drugs, gases, and pathogens toward …
NL van der Meijs, MA Travecedo… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction CLEC10A is a C-type lectin receptor that specifically marks the conventional dendritic cell subsets two and three (cDC2 and DC3). It has a unique recognition profile of …
R Ayyalasomayajula, I Boneva, D Ormaza… - …, 2024 - Wiley Online Library
Interactions between the tumor‐associated carbohydrate antigens of Mucin 1 (MUC1) and the carbohydrate‐binding proteins, lectins, often lead to the creation of a pro‐tumor …
I Radziejewska - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Glycosylation of cancerous epithelial MUC1 protein is specifically altered in comparison to that which is presented by healthy cells. One of such changes is appearing tumor …
YN Singh, D Ormaza, A Massetti… - ACS Chemical …, 2021 - ACS Publications
The amyloid-β precursor protein (APP) undergoes proteolytic cleavage by α-, β-, and γ- secretases, to determine its fate in Alzheimer's disease (AD) pathogenesis. Recent findings …
ML McKeague, J Lohmueller, MT Dracz, N Saadallah… - Antibodies, 2024 - mdpi.com
Background/Objectives: Mucin-1 (MUC1) is a transmembrane glycoprotein that is overexpressed and hypoglycosylated in premalignant and malignant epithelial cells …
Y Li, L Wang, L Ding, H Ju - Targets, 2023 - mdpi.com
Cell-surface glycans are abundant and complex and play a critical role in maintaining protein stability, regulating cell behavior, and participating in cell communication. Obtaining …