Tissue based research requires a background in human and veterinary pathology,
developmental biology, anatomy, as well as molecular and cellular biology. This type of c …

Classical zinc finger (ZF) domains were thought to be confined to the eukaryotic kingdom
until the transcriptional regulator Ros protein was identified in Agrobacterium tumefaciens …

Bacterial adaptation is largely shaped by horizontal gene transfer, xenogeneic silencing
mediated by lineage-specific DNA bridgers (H-NS, Lsr2, MvaT and Rok), and various anti …

Foreign AT-rich genes drive bacterial adaptation to new niches while challenging the
existing regulation network. Here we report that MucR, a conserved regulator in α …

Proteins of the MucR/Ros family play a crucial role in bacterial infection or symbiosis with
eukaryotic hosts. MucR from Sinorhizobium meliloti plays a regulatory role in establishing …

The ubiquitous bacterial second messenger c-di-GMP is intensively studied in pathogens
but less so in mutualistic bacteria. Here, we report a genome-wide investigation of functional …

Zinc ion binding is a principal event in the achievement of the correct fold in classical zinc
finger domains since the motif is largely unfolded in the absence of metal. In the case of a …

MucR is a member of the Ros/MucR family of prokaryotic zinc-finger proteins found in the α-
proteobacteria which regulate the expression of genes required for the successful …

The protein MucR from Brucella abortus has been described as a transcriptional regulator of
many virulence genes. It is a member of the Ros/MucR family comprising proteins that …

Ros/MucR is a widespread family of bacterial zinc-finger (ZF) containing proteins that
integrate multiple functions such as virulence, symbiosis and/or cell cycle transcription. NMR …