Applications of deep learning and reinforcement learning to biological data

M Mahmud, MS Kaiser, A Hussain… - IEEE transactions on …, 2018 - ieeexplore.ieee.org
Rapid advances in hardware-based technologies during the past decades have opened up
new possibilities for life scientists to gather multimodal data in various application domains …

Toward an autonomous brain machine interface: integrating sensorimotor reward modulation and reinforcement learning

BT Marsh, VSA Tarigoppula, C Chen… - Journal of …, 2015 - Soc Neuroscience
For decades, neurophysiologists have worked on elucidating the function of the cortical
sensorimotor control system from the standpoint of kinematics or dynamics. Recently …

Neuroplasticity of the sensorimotor cortex during learning

JT Francis, W Song - Neural plasticity, 2011 - Wiley Online Library
We will discuss some of the current issues in understanding plasticity in the sensorimotor
(SM) cortices on the behavioral, neurophysiological, and synaptic levels. We will focus our …

Neural control of a tracking task via attention-gated reinforcement learning for brain-machine interfaces

Y Wang, F Wang, K Xu, Q Zhang… - IEEE Transactions on …, 2014 - ieeexplore.ieee.org
Reinforcement learning (RL)-based brain machine interfaces (BMIs) enable the user to learn
from the environment through interactions to complete the task without desired signals …

Quantized attention-gated kernel reinforcement learning for brain–machine interface decoding

F Wang, Y Wang, K Xu, H Li, Y Liao… - IEEE transactions on …, 2015 - ieeexplore.ieee.org
Reinforcement learning (RL)-based decoders in brain-machine interfaces (BMIs) interpret
dynamic neural activity without patients' real limb movements. In conventional RL, the goal …

Neural decoders using reinforcement learning in brain machine interfaces: A technical review

B Girdler, W Caldbeck, J Bae - Frontiers in Systems Neuroscience, 2022 - frontiersin.org
Creating flexible and robust brain machine interfaces (BMIs) is currently a popular topic of
research that has been explored for decades in medicine, engineering, commercial, and …

Clustering neural patterns in kernel reinforcement learning assists fast brain control in brain-machine interfaces

X Zhang, C Libedinsky, R So… - IEEE Transactions on …, 2019 - ieeexplore.ieee.org
Neuroprosthesis enables the brain control on the external devices purely using neural
activity for paralyzed people. Supervised learning decoders recalibrate or re-fit the …

Reward expectation modulates local field potentials, spiking activity and spike-field coherence in the primary motor cortex

J An, T Yadav, JP Hessburg, JT Francis - eneuro, 2019 - eneuro.org
Reward modulation (M1) could be exploited in developing an autonomously updating brain-
computer interface (BCI) based on a reinforcement learning (RL) architecture. For an …

Restoring behavior via inverse neurocontroller in a lesioned cortical spiking model driving a virtual arm

S Dura-Bernal, K Li, SA Neymotin, JT Francis… - Frontiers in …, 2016 - frontiersin.org
Neural stimulation can be used as a tool to elicit natural sensations or behaviors by
modulating neural activity. This can be potentially used to mitigate the damage of brain …

Cortical spiking network interfaced with virtual musculoskeletal arm and robotic arm

S Dura-Bernal, X Zhou, SA Neymotin… - Frontiers in …, 2015 - frontiersin.org
Embedding computational models in the physical world is a critical step towards
constraining their behavior and building practical applications. Here we aim to drive a …