The role of Caenorhabditis elegans in the discovery of natural products for healthy aging

B Kirchweger, J Zwirchmayr, U Grienke… - Natural Product …, 2023 - pubs.rsc.org
Covering: 2012 to 2023 The human population is aging. Thus, the greatest risk factor for
numerous diseases, such as diabetes, cancer and neurodegenerative disorders, is …

Application of 3Rs in Caenorhabditis elegans Research for the Identification of Health-Promoting Natural Products

M Redl, A Shayegan, JM Rollinger - Planta Medica, 2024 - thieme-connect.com
The average age of the population is increasing worldwide, which has a profound impact on
our society. This leads to an increasing demand for medicines and requires the …

Deciphering the 4′,7‐Dihydroxy‐3′‐Methylflavone from Boerhavia, Agonist/Antagonist Interactions Against 5‐HT2 Receptors using Homology Modeling …

P Salaria, DG Niharika, SRN N… - Chemistry & …, 2024 - Wiley Online Library
Seizures, depression, and anxiety are neurological disorders that affected innumerable
people worldwide. Recent research has revealed that targeting 5‐hydroxytryptamine 2 (5 …

A Comprehensive Description of the Anatomy and Histochemistry of Psychotria capillacea (Müll. Arg.) Standl. and an Investigation into Its Anti-Inflammatory Effects in …

ASN Formagio, W Vilegas, CAL Kassuya… - Pharmaceuticals, 2024 - mdpi.com
Species of the genus Psychotria are used in popular medicine for pain, inflammatory
symptoms, and mental disorders. Psychotria capillacea (Müll. Arg.) Standl.(Rubiaceae) is …

Integration of semi-automatic tools for assessing health promoting effects of natural products in C. elegans

M Redl, JM Rollinger - Planta Medica, 2023 - thieme-connect.com
The average life expectancy of the human population is constantly increasing. According to
the WHO, the number of people aged 80 years or older will be tripled by the year 2050 …

[PDF][PDF] Natural Product Reports

B Kirchweger, J Zwirchmayr, U Grienke, JM Rollinger - uscholar.univie.ac.at
The human population is aging. Thus, the greatest risk factor for numerous diseases, such
as diabetes, cancer and neurodegenerative disorders, is increasing worldwide. Age-related …

Short Lecture “From in silico to in vivo: Psychotria nemorosa alkaloids counter protein toxicity in Caenorhabditis elegans”

B Kirchweger, LC Klein-Junior, D Pretsch… - Planta …, 2022 - thieme-connect.com
Usually, novel natural products are isolated in small amounts. This makes it difficult to
explore their pharmacological targets in vitro and explore their effects in vivo. Hence …

Implementierung semiautomatischer Messgeräte zur Austestung von Naturstoffen in C. elegans

M Redl, JM Rollinger - Zeitschrift für Phytotherapie, 2023 - thieme-connect.com
Die durchschnittliche Lebenserwartung der menschlichen Bevölkerung steigt stetig. Altern
wird von einer kontinuierlichen Verschlechterung des allgemeinen Gesundheitszustands …