Molecular epidemiology of HIV-1 infection in Europe: An overview

A Beloukas, A Psarris, P Giannelou, E Kostaki… - Infection, Genetics and …, 2016 - Elsevier
Abstract Human Immunodeficiency Virus type 1 (HIV-1) is characterised by vast genetic
diversity. Globally circulating HIV-1 viruses are classified into distinct phylogenetic strains …

The origin and molecular epidemiology of HIV

M Peeters, M Jung, A Ayouba - Expert review of anti-infective …, 2013 - Taylor & Francis
HIV-1 in humans resulted from at least four cross-species transmissions of simian
immunodeficiency viruses (SIVs) from chimpanzees and gorillas in West Central Africa …

COMET: adaptive context-based modeling for ultrafast HIV-1 subtype identification

D Struck, G Lawyer, AM Ternes, JC Schmit… - Nucleic acids …, 2014 - academic.oup.com
Viral sequence classification has wide applications in clinical, epidemiological, structural
and functional categorization studies. Most existing approaches rely on an initial alignment …

[HTML][HTML] Automated subtyping of HIV-1 genetic sequences for clinical and surveillance purposes: performance evaluation of the new REGA version 3 and seven other …

AC Pineda-Peña, NR Faria, S Imbrechts, P Libin… - Infection, genetics and …, 2013 - Elsevier
Background To investigate differences in pathogenesis, diagnosis and resistance pathways
between HIV-1 subtypes, an accurate subtyping tool for large datasets is needed. We aimed …

Impact of Early Pandemic Stage Mutations on Molecular Dynamics of SARS-CoV-2 Mpro

O Sheik Amamuddy, GM Verkhivker… - Journal of chemical …, 2020 - ACS Publications
A new coronavirus (SARS-CoV-2) is a global threat to world health and economy. Its dimeric
main protease (Mpro), which is required for the proteolytic cleavage of viral precursor …

VIRULIGN: fast codon-correct alignment and annotation of viral genomes

PJK Libin, K Deforche, AB Abecasis, K Theys - Bioinformatics, 2019 - academic.oup.com
Virus sequence data are an essential resource for reconstructing spatiotemporal dynamics
of viral spread as well as to inform treatment and prevention strategies. However, the …

Consequences of HIV infection in the bone marrow niche

CL Herd, J Mellet, T Mashingaidze, C Durandt… - Frontiers in …, 2023 - frontiersin.org
Dysregulation of the bone marrow niche resulting from the direct and indirect effects of HIV
infection contributes to haematological abnormalities observed in HIV patients. The bone …

[HTML][HTML] HIV-1 subtype B: Traces of a pandemic

DM Junqueira, SE de Matos Almeida - Virology, 2016 - Elsevier
Human migration is a major process that shaped the origin and dissemination of HIV. Within
HIV-1, subtype B (HIV-1B) is the most disseminated variant and it is assumed to be the …

[HTML][HTML] The global spread of HIV-1 subtype B epidemic

G Magiorkinis, K Angelis, I Mamais… - Infection, genetics and …, 2016 - Elsevier
Human immunodeficiency virus type 1 (HIV-1) was discovered in the early 1980s when the
virus had already established a pandemic. For at least three decades the epidemic in the …

The impact of HIV-1 within-host evolution on transmission dynamics

K Theys, P Libin, AC Pineda-Pena, A Nowe… - Current opinion in …, 2018 - Elsevier
Highlights•HIV-1 within-host evolution is short-sighted and favours more virulent
viruses.•Systemic HIV-1 infection is mainly established by a single variant …