The physiological effects of vasopressin as a peripheral hormone were first reported more
than 100 years ago. However, it was not until the first immunocytochemical studies were …

Addiction is a widespread public health issue with social and economic ramifications.
Substance abuse disorders are often accompanied by disruptions in circadian rhythms …

Circadian rhythms are prominent in many physiological and behavioral functions. Circadian
disruptions either by environmental or molecular perturbation can have profound health …

Background Circadian rhythm disturbances are frequently found in depressed subjects.
Although it has been presumed that these disturbances may reflect a disorder of the …

Arginine vasopressin (AVP) is a cyclic nonapeptide synthesized exclusively by
neurosecretory cells of the central nervous system (CNS). Two functionally distinct …

Two peptides [NAPVSIPQ (NAP) and SALLRSIPA (ADNF-9)], that are associated with novel
glial proteins regulated by vasoactive intestinal peptide, are shown now to provide protective …

Previous data revealed that numerous neurons in the supraoptic nucleus degenerate after
prolonged ethanol exposure, and that the surviving neurons increase their activity in order to …

Mice with a mutation in the Clock gene (ClockΔ19) exhibit increased preference for stimulant
rewards and sucrose. They also have an increase in dopaminergic activity in the ventral …

We have examined if long-term (13 months) alcohol consumption and the same treatment
followed by a 6-week withdrawal period cause different neuropathological changes in rats …

Background Arginine vasopressin (VP) has been implicated in a number of neuropsychiatric
disorders with an emphasis on situations where stress increased the severity of the disorder …