Small molecule grp94 inhibitors block dengue and Zika virus replication

HA Rothan, Y Zhong, MA Sanborn, TC Teoh, J Ruan… - Antiviral Research, 2019 - Elsevier
Two major flaviviruses, dengue virus (DENV) and Zika virus (ZIKV), cause severe health and
economic burdens worldwide. Recently, genome-wide screenings have uncovered the …

Early dengue virus interactions: the role of dendritic cells during infection

HFS Souza, B da Silva Almeida, SB Boscardin - Virus research, 2016 - Elsevier
Dengue is an acute infectious disease caused by dengue virus (DENV) that affects
approximately 400 million people annually, being the most prevalent human arthropod …

Climate induced virus generated communicable diseases: management issues and failures

RK Upadhyay - Journal of Atmospheric Science Research, 2021 - journals.bilpubgroup.com
In the present review article human diseases caused by various groups of pathogens have
been explained with its etiology, epidemiology and treatment. In addition, effect of climatic …

Mechanism of ATP hydrolysis by the Zika virus helicase

X Yang, C Chen, H Tian, H Chi, Z Mu… - The FASEB …, 2018 - Wiley Online Library
During its life cycle, Zika virus (ZIKV), an arthropod‐borne flavivirus that is associated with
Guillain‐Barré syndrome and causes microencephaly in fetuses and newborn children …

Helicase domain of West Nile virus NS3 protein plays a role in inhibition of type I interferon signalling

YX Setoh, P Periasamy, NYG Peng, AA Amarilla… - Viruses, 2017 - mdpi.com
West Nile virus (WNV) is a neurotropic flavivirus that can cause encephalitis in mammalian
and avian hosts. In America, the virulent WNV strain (NY99) is causing yearly outbreaks of …

Viremia and Inflammatory Cytokines in Dengue: Interleukin-2 as a Biomarker of Infection, and Interferon-α and-γ as Markers of Primary versus Secondary Infection

TB de Arruda, L Bavia, ALP Mosimann, MN Aoki… - Pathogens, 2023 - mdpi.com
The pathogenesis of Dengue virus (DENV) infection is complex and involves viral replication
that may trigger an inflammatory response leading to severe disease. Here, we investigated …

Integrated analysis of microarray studies to identify novel diagnostic markers in bladder pain syndrome/interstitial cystitis with Hunner lesion

XF Cheng, ZH Zeng, W Deng, YF Liu… - … Journal of General …, 2022 - Taylor & Francis
Background The aim of this study was to identify novel genetic features of Hunner's lesion
interstitial cystitis (HIC) via comprehensive analysis of the Gene Expression Omnibus (GEO) …

Biosensors for Point Mutation Detection

H Jiang, H Xi, M Juhas, Y Zhang - Frontiers in Bioengineering and …, 2021 - frontiersin.org
Point mutations referring to a single base pair change, have a profound effect on the
phenotype and play important roles in the variety of diseases (Nasis et al., 2004; Silva et al …

Analysis of Skin Neoplasms' Raman Spectra Using the Lorentz Approximation Method: Pilot Studies

IN Saraeva, EN Rimskaya, AB Timurzieva, AV Gorevoy… - JETP Letters, 2024 - Springer
Confocal Raman microspectroscopy provides the ability to diagnose cancer by quantitatively
analyzing spectral features and identifying underlying biochemical changes. The …

Reverse Genetics of Dengue Virus

JVJ Silva Júnior, ANMR da Silva… - Reverse Genetics of …, 2023 - Springer
Dengue virus (DENV) is one of the most important and widespread arthropod-borne viruses,
causing millions of infections over the years. Considering its epidemiological importance …