Nephrotic syndrome is a highly prevalent disease that is associated with high morbidity
despite notable advances in its treatment. Many of the complications of nephrotic syndrome …

Childhood nephrotic syndromes are most commonly caused by one of two idiopathic
diseases: minimal-change nephrotic syndrome (MCNS) and focal segmental …

Lipotoxicity is characterized by the ectopic accumulation of lipids in organs different from
adipose tissue. Lipotoxicity is mainly associated with dysfunctional signaling and insulin …

Background: Statins have uncertain benefits in persons with chronic kidney disease (CKD)
because individual trials may have insufficient power to determine whether treatment effects …

Background The effects of statin administration on kidney disease outcomes remain
controversial. We undertook a systematic review and meta-analysis to assess the efficacy of …

In Japan, original researches on nephrotic syndrome (NS) were initially performed by the
Ministry of Health, Labour and Welfare (MHLW) NS research group. The first definition of NS …

It is widely accepted that proteinuria reduction is an appropriate therapeutic goal in chronic
proteinuric kidney disease. Based on large randomized controlled clinical trials (RCT), ACE …

Dyslipidemia is classified into primary and secondary types. Primary dyslipidemia is
basically inherited and caused by single or multiple gene mutations that result in either …

Patients with chronic kidney disease (CKD) are much more likely to die of cardiovascular
disease than end-stage renal disease. Dyslipidemia is highly prevalent in patients with CKD …

Previous studies showed that statins reduce the progression of kidney function decline and
proteinuria, but whether specific types of statins are more beneficial than others remains …