Background Haemoglobin genotype screening at prenatal care offers women an opportunity
to be aware of their genotype, receive education on sickle cell disease (SCD) and may …

Objective To determine the uptake, knowledge level and attitude towards sickle cell trait
screening in students aged 18 to 35 years in a Ugandan university. Methods This was a …

Sickle cell disease is a genetic disorder characterised by the tendency of haemoglobin to
polymerise and deform red blood cells to a sickle or crescent shape; this consequently …

More than 24% of Nigerians are carriers of the sickle cell gene, while about 2% of all the
newborns in Nigeria are born with the sickle cell disease. The disease is a lifelong cause of …

Background: The prevalence of sickle cell anemia has been shown to be on the increase in
Nigeria. Therefore preventive measures like premarital genotype screening have been …

Background: Sickle cell disease is a condition in which an individual inherit two abnormal
haemoglobin genes from both parents βs/βs (HbSS) resulting in pathological state which is …

Premarital sickle cell genetic screening is a test that determines the genotype of the
intending couple before marriage. As a result, counseling is given before and after the test …

Background: Sickle cell disease is a major genetic disease with the greatest burden in sub-
Saharan Africa, of which Nigeria is the epicenter. Premarital genotype screening for sickle …

Nigeria has the highest number of homozygous sickle cell disease (HbSS) in the world with
a prevalence of 1.3%. About a quarter of Nigerian populations (24%) are carriers of the …

Marital decision following premarital genotype screening is a key to prevent the risk of
having children with Sickle cell disease. Sickle cell disorder is one of the genetic diseases …