Effects of engineered nanoparticles on the innate immune system

Y Liu, J Hardie, X Zhang, VM Rotello - Seminars in immunology, 2017 - Elsevier
Engineered nanoparticles (NPs) have broad applications in industry and nanomedicine.
When NPs enter the body, interactions with the immune system are unavoidable. The innate …

Adjuvants and delivery systems based on polymeric nanoparticles for mucosal vaccines

Z Jin, S Gao, X Cui, D Sun, K Zhao - International journal of pharmaceutics, 2019 - Elsevier
Most pathogens enter the body through mucosal surfaces. Therefore, vaccination through
the mucosal route can greatly enhance the mucosal immune response. Vaccination via the …

Microneedle-based drug delivery: Materials of construction

S Bhatnagar, PR Gadeela, P Thathireddy… - Journal of Chemical …, 2019 - Springer
Microneedle-based drug delivery has attracted researchers' attention over the last decade.
The material of construction of microneedles has emerged as a critical factor influencing …

TLR4-based immunotherapeutics in cancer: a review of the achievements and shortcomings

MA Shetab Boushehri, A Lamprecht - Molecular pharmaceutics, 2018 - ACS Publications
Toll-like Receptor 4 (TLR4) agonists have had a long journey in the field of cancer
immunotherapy. Nevertheless, despite the remarkable number of the TLR4 ligands that …

Nanovaccines and their mode of action

M Zaman, MF Good, I Toth - Methods, 2013 - Elsevier
Nanosized particles including nanovaccines are a novel approach to the development of
vaccines to combat diseases. Nanovaccines have the promise to utilize the immune system …

Immunomodulation of nanoparticles in nanomedicine applications

Q Jiao, L Li, Q Mu, Q Zhang - BioMed research international, 2014 - Wiley Online Library
Nanoparticles (NPs) have promising applications in medicine. Immune system is an
important protective system to defend organisms from non‐self matters. NPs interact with the …

Current progress and challenges in the study of adjuvants for oral vaccines

B Ou, Y Yang, H Lv, X Lin, M Zhang - BioDrugs, 2023 - Springer
Over the past 20 years, a variety of potential adjuvants have been studied to enhance the
effect of oral vaccines in the intestinal mucosal immune system; however, no licensed …

Nanoparticle impact on innate immune cell pattern-recognition receptors and inflammasomes activation

AL Silva, C Peres, J Conniot, AI Matos, L Moura… - Seminars in …, 2017 - Elsevier
Nanotechnology-based strategies can dramatically impact the treatment, prevention and
diagnosis of a wide range of diseases. Despite the unprecedented success achieved with …

Advances of Nanotechnology Toward Vaccine Development Against Animal Infectious Diseases

X Wang, X Gao, L Wang, J Lin… - Advanced Functional …, 2023 - Wiley Online Library
Vaccines are the most effective means of controlling infectious diseases. Increasingly
epidemics have driven the development of vaccines for human use. However, insufficient …

Nanotechnology as a platform for the development of injectable parenteral formulations: a comprehensive review of the know-hows and state of the art

MA Shetab Boushehri, D Dietrich, A Lamprecht - Pharmaceutics, 2020 - mdpi.com
Within recent decades, the development of nanotechnology has made a significant
contribution to the progress of various fields of study, including the domains of medical and …