Central nervous system neurons communicate via fast synaptic transmission mediated by
ligand-gated ion channel (LGIC) receptors and slower neuromodulation mediated by G …

Understanding how neuronal activity patterns in the brain correlate with complex behavior is
one of the primary goals of modern neuroscience. Chemical transmission is the major way of …

Genetically encoded fluorescent voltage indicators are ideally suited to reveal the
millisecond-scale interactions among and between targeted cell populations. However …

Widefield imaging with genetically encoded voltage indicators (GEVIs) is a promising
approach for understanding the role of large cortical networks in the neural coding of …

Neurophotonics was launched in 2014 coinciding with the launch of the BRAIN Initiative
focused on development of technologies for advancement of neuroscience. For the last …

Simple Summary We review advances in the properties of calcium sensors, microscopy, and
data analysis that have brought about the ability to image large contiguous regions of the …

The first member and eponym of the rhodopsin family was identified in the 1930s as the
visual pigment of the rod photoreceptor cell in the animal retina. It was found to be a …

Confirming the direct link between neural circuit activity and animal behavior has been a
principal aim of neuroscience. The genetically encoded calcium indicator (GECI), which …

Brain functions are fundamental for the survival of organisms, and they are supported by
neural circuits consisting of a variety of neurons. To investigate the function of neurons at the …

Neural circuits and the cells that comprise them represent the functional units of the brain.
Circuits relay and process sensory information, maintain homeostasis, drive behaviors, and …