Versatile function of NF-ĸB in inflammation and cancer

Q Ma, S Hao, W Hong, V Tergaonkar, G Sethi… - … Hematology & Oncology, 2024 - Springer
Nuclear factor-kappaB (NF-ĸB) plays a crucial role in both innate and adaptive immune
systems, significantly influencing various physiological processes such as cell proliferation …

Current progress of ferroptosis study in hepatocellular carcinoma

X Zhu, X Sha, Y Zang, Q Ren, S Zhang… - International …, 2024 - pmc.ncbi.nlm.nih.gov
Ferroptosis, an emerging type of programmed cell death, is initiated by iron-dependent and
excessive ROS-mediated lipid peroxidation, which eventually leads to plasma membrane …

[HTML][HTML] Ferroptosis in cancer: epigenetic control and therapeutic opportunities

R Veglia Tranchese, S Battista, L Cerchia, M Fedele - Biomolecules, 2024 - mdpi.com
Ferroptosis, an iron-dependent form of regulated cell death driven by lipid peroxidation, has
emerged as a critical pathway in cancer biology. This review delves into the epigenetic …

[HTML][HTML] Inhibition of NF-κB signaling unveils novel strategies to overcome drug resistance in cancers

Y Li, B Zhao, J Peng, H Tang, S Wang, S Peng… - Drug Resistance …, 2024 - Elsevier
Drug resistance in cancer remains a major challenge in oncology, impeding the
effectiveness of various treatment modalities. The nuclear factor-kappa B (NF-κB) signaling …

Programmed cell death in hepatocellular carcinoma: mechanisms and therapeutic prospects

X Wu, J Cao, X Wan, S Du - Cell Death Discovery, 2024 - nature.com
Hepatocellular Carcinoma (HCC), the most common primary liver cancer, ranks as the third
most common cause of cancer-related deaths globally. A deeper understanding of the cell …

The mechanism of ferroptosis and its related diseases

S Feng, D Tang, Y Wang, X Li, H Bao, C Tang… - Molecular …, 2023 - Springer
Ferroptosis, a regulated form of cellular death characterized by the iron-mediated
accumulation of lipid peroxides, provides a novel avenue for delving into the intersection of …

Aristolochic acids-hijacked p53 promotes liver cancer cell growth by inhibiting ferroptosis

C Hou, Y Suo, P Lv, H Yuan, L Zhao, Y Wang… - Acta Pharmacologica …, 2024 - nature.com
Aristolochic acids (AAs) have been identified as a significant risk factor for hepatocellular
carcinoma (HCC). Ferroptosis is a type of regulated cell death involved in the tumor …

[HTML][HTML] Cold atmospheric plasma enhances SLC7A11-mediated ferroptosis in non-small cell lung cancer by regulating PCAF mediated HOXB9 acetylation

C Zhang, H Liu, X Li, N Xiao, H Chen, H Feng, Y Li… - Redox Biology, 2024 - Elsevier
Lung cancer is a leading cause of cancer death worldwide, with high incidence and poor
survival rates. Cold atmospheric plasma (CAP) technology has emerged as a promising …

Iron accumulation and lipid peroxidation: implication of ferroptosis in hepatocellular carcinoma

X Li, F Meng, H Wang, L Sun, S Chang, G Li… - Frontiers in …, 2024 - frontiersin.org
Ferroptosis is a type of controlled cell death caused by lipid peroxidation, which results in
the rupture of the cell membrane. ferroptosis has been repeatedly demonstrated over the …

Ferroptosis: Potential opportunities for natural products in cancer therapy

A Nie, C Shen, Z Zhou, J Wang, B Sun… - Phytotherapy …, 2024 - Wiley Online Library
Cancer cells often exhibit defects in the execution of cell death, resulting in poor clinical
outcomes for patients with many cancer types. Ferroptosis is a newly discovered form of …