Epidemiology, causes, and treatment of epilepsy in sub-Saharan Africa

A Ba-Diop, B Marin, M Druet-Cabanac… - The Lancet …, 2014 - thelancet.com
Epilepsy is a common neurological disease in tropical countries, particularly in sub-Saharan
Africa. Previous work on epilepsy in sub-Saharan Africa has shown that many cases are …

Reducing neurodevelopmental disorders and disability through research and interventions

MJ Boivin, AM Kakooza, BC Warf, LL Davidson… - Nature, 2015 - nature.com
We define neurodevelopment as the dynamic inter-relationship between genetic, brain,
cognitive, emotional and behavioural processes across the developmental lifespan …

Parasitic, bacterial, viral, immune-mediated, metabolic and nutritional factors associated with nodding syndrome

AWD Edridge, G Abd-Elfarag, M Deijs… - Brain …, 2023 - academic.oup.com
Nodding syndrome is a neglected, disabling and potentially fatal epileptic disorder of
unknown aetiology affecting thousands of individuals mostly confined to Eastern sub …

Nodding syndrome may be an autoimmune reaction to the parasitic worm Onchocerca volvulus

TP Johnson, R Tyagi, PR Lee, MH Lee… - Science translational …, 2017 - science.org
Nodding syndrome is an epileptic disorder of unknown etiology that occurs in children in
East Africa. There is an epidemiological association with Onchocerca volvulus, the parasitic …

Neuroinflammation and not tauopathy is a predominant pathological signature of nodding syndrome

A Hotterbeekx, M Lammens, R Idro… - … of Neuropathology & …, 2019 - academic.oup.com
Nodding syndrome (NS) is an epileptic disorder occurring in children in African
onchocerciasis endemic regions. Here, we describe the pathological changes in 9 …

[HTML][HTML] Mapping, associated factors, and pathophysiology of nodding syndrome in Africa: A systematic review

S Metanmo, D Dossa, DN Ahmat, AS Winkler… - …, 2024 - karger.com
Introduction: Nodding syndrome (NS) remains a poorly understood disorder. For a long time,
it has been thought to be restricted to East Africa; however, cases in Central Africa have …

Nodding syndrome in Uganda is a tauopathy

MS Pollanen, S Onzivua, J Robertson… - Acta …, 2018 - Springer
Nodding syndrome is an epidemic neurologic disorder of unknown cause that affects
children in the subsistence-farming communities of East Africa. We report the …

Tauopathy and movement disorders—unveiling the chameleons and mimics

J Ganguly, M Jog - Frontiers in Neurology, 2020 - frontiersin.org
The spectrum of tauopathy encompasses heterogenous group of neurodegenerative
disorders characterized by neural or glial deposition of pathological protein tau. Clinically …

Onchocerciasis‐associated epilepsy: From recent epidemiological and clinical findings to policy implications

R Colebunders, AK Njamnshi, M van Oijen… - Epilepsia …, 2017 - Wiley Online Library
A high prevalence of epilepsy is reported in many onchocerciasis‐endemic regions. In this
paper we discuss recent epidemiological and clinical aspects as well as public health …

Nakalanga syndrome: clinical characteristics, potential causes, and its relationship with recently described nodding syndrome

K Föger, G Gora-Stahlberg, J Sejvar… - PLOS neglected …, 2017 - journals.plos.org
Nakalanga syndrome is a condition that was described in Uganda and various other African
countries decades ago. Its features include growth retardation, physical deformities …