The past several decades have witnessed great progress in the understanding of the high-
order structure of biomacromolecules. Currently, it is well-recognized that folding of proteins …

Antimicrobial peptides (AMPs) provide protection against a variety of pathogenic bacteria
and are, therefore, an important part of the innate immune system. Over the past decade …

Synthetic macromolecular antimicrobials are a highly promising class of therapeutics with
immense potential for combating multidrug resistant microbes. In contrast to conventional …

Based on torsion angle distributions of frequently occurring substructures, conformation
preferences of druglike molecules are presented, accompanied by a review of the relevant …

The emergence of drug-resistant bacteria has compromised the use of many conventional
antibiotics, leading to heightened interest in a variety of antimicrobial peptides. Although …

Infectious diseases and antibiotic resistance are now considered the most imperative global
healthcare problem. In the search for new treatments, host defense, or antimicrobial …

The JOYCE program is augmented with several new features, including the user friendly
ULYSSES GUI, the possibility of complete excited state parameterization and a more flexible …

The combined utility of many one and two dimensional NMR methodologies and DFT-based
theoretical calculations have been exploited to detect the intramolecular hydrogen bond …

Elucidation of the ligand/protein binding interaction is of paramount relevance in
pharmacology to increase the success rate of drug design. To this end, a number of …

Abstract N‐Centred benzene‐1, 3, 5‐tricarboxamides (N‐BTAs) composed of chiral and
achiral alkyl substituents were synthesised and their solid‐state behaviour and self …