[HTML][HTML] Implications of physics, chemistry and biology for dosimetry calculations using theranostic pairs

C Miller, J Rousseau, CF Ramogida, A Celler… - Theranostics, 2022 - ncbi.nlm.nih.gov
Theranostics is an emerging paradigm that combines imaging and therapy in order to
personalize patient treatment. In nuclear medicine, this is achieved by using …

[HTML][HTML] Therapeutic radionuclides in nuclear medicine: current and future prospects

CH Yeong, M Cheng, KH Ng - Journal of Zhejiang University …, 2014 - ncbi.nlm.nih.gov
The potential use of radionuclides in therapy has been recognized for many decades. A
number of radionuclides, such as iodine-131 (131 I), phosphorous-32 (32 P), strontium-90 …

MIRD pamphlet no. 23: quantitative SPECT for patient-specific 3-dimensional dosimetry in internal radionuclide therapy

YK Dewaraja, EC Frey, G Sgouros… - Journal of Nuclear …, 2012 - Soc Nuclear Med
In internal radionuclide therapy, a growing interest in voxel-level estimates of tissue-
absorbed dose has been driven by the desire to report radiobiologic quantities that account …

Spect/ct

AK Buck, S Nekolla, S Ziegler, A Beer… - Journal of Nuclear …, 2008 - Soc Nuclear Med
In view of the commercial success of integrated PET/CT scanners, there is an increasing
interest in comparable SPECT/CT systems. SPECT in combination with CT enables a direct …

Subacute haematotoxicity after PRRT with 177Lu-DOTA-octreotate: prognostic factors, incidence and course

H Bergsma, MW Konijnenberg, BLR Kam… - European journal of …, 2016 - Springer
Purpose In peptide receptor radionuclide therapy (PRRT), the bone marrow (BM) is one of
the dose-limiting organs. The accepted dose limit for BM is 2 Gy, adopted from 131 I …

Absolute quantification in SPECT

P Ritt, H Vija, J Hornegger, T Kuwert - European journal of nuclear …, 2011 - Springer
Single-photon emission computed tomography (SPECT) allows the three-dimensional
visualization of radioactivity within the human body and is widely used for clinical purposes …

Feasibility of 90Y TOF PET-based dosimetry in liver metastasis therapy using SIR-Spheres

R Lhommel, L Van Elmbt, P Goffette… - European journal of …, 2010 - Springer
Purpose 90 Y-labelled compounds used in targeted radiotherapy are usually imaged with
SPECT by recording the bremsstrahlung X-rays of the β decay. The continuous shape of the …

Image-guided personalized predictive dosimetry by artery-specific SPECT/CT partition modeling for safe and effective 90Y radioembolization

YH Kao, AEH Tan, MC Burgmans, FG Irani… - Journal of Nuclear …, 2012 - Soc Nuclear Med
Compliance with radiobiologic principles of radionuclide internal dosimetry is fundamental
to the success of 90Y radioembolization. The artery-specific SPECT/CT partition model is an …

A multicentre and multi-national evaluation of the accuracy of quantitative Lu-177 SPECT/CT imaging performed within the MRTDosimetry project

J Tran-Gia, AM Denis-Bacelar, KM Ferreira… - EJNMMI physics, 2021 - Springer
Purpose Patient-specific dosimetry is required to ensure the safety of molecular radiotherapy
and to predict response. Dosimetry involves several steps, the first of which is the …

[HTML][HTML] A perspective on the radiopharmaceutical requirements for imaging and therapy of glioblastoma

J Bolcaen, J Kleynhans, S Nair, J Verhoeven… - Theranostics, 2021 - ncbi.nlm.nih.gov
Despite numerous clinical trials and pre-clinical developments, the treatment of glioblastoma
(GB) remains a challenge. The current survival rate of GB averages one year, even with an …