A person suspected of having Alzheimer's disease (AD) is clinically diagnosed for the
presence of principal biomarkers, especially misfolded amyloid-beta (Aβ) and tau proteins in …

When small molecules or proteins are injected into live animals, their physical and chemical
properties will significantly affect pharmacokinetics, tissue penetration, and the ultimate …

Understanding the release kinetics of siRNA from nanocarriers, their cellular uptake, their in
vivo biodistribution and pharmacokinetics is a fundamental prerequisite for efficient …

One is their low emissive quantum yields, which are only a few percent even for nanotubes
with very low defect levels. This drawback is partly compensated by exceptional …

We developed a neutrophil elastase‐specific near‐infrared fluorescence imaging agent,
which, combined with fluorescence molecular tomographic imaging, allowed us to detect …

Spinal cord injury (SCI) is a devastating condition causing the loss of sensory and motor
functions. SCI pathology is multifaceted, encompassing inflammation, scarring, neuronal …

Background Experimental autoimmune encephalomyelitis (EAE) is an animal model that
captures many of the hallmarks of human multiple sclerosis (MS), including blood–brain …

Lung samples were prepared to investigate the perturbing effects of light absorption for
quantifying the fluorescence signal of aluminum phthalocyanine tetrasulfonic acid (AlPCS) …

Fluorescence molecular imaging (MI) is an important concept in preclinical research that
focuses on the visualization of cellular and biological function in a non-invasive fashion to …

The adoption of axially oriented line illumination patterns for fluorescence excitation in small
animals for fluorescence surface imaging (FSI) and fluorescence optical tomography (FOT) …