Cell–extracellular matrix mechanotransduction in 3D

A Saraswathibhatla, D Indana… - Nature Reviews Molecular …, 2023 - nature.com
Mechanical properties of extracellular matrices (ECMs) regulate essential cell behaviours,
including differentiation, migration and proliferation, through mechanotransduction. Studies …

Hyaluronic acid: A key ingredient in the therapy of inflammation

A Marinho, C Nunes, S Reis - Biomolecules, 2021 - mdpi.com
Hyaluronic acid (HA) is a natural polymer, produced endogenously by the human body,
which has unique physicochemical and biological properties, exhibiting desirable …

Engineered materials for organoid systems

MJ Kratochvil, AJ Seymour, TL Li, SP Paşca… - Nature Reviews …, 2019 - nature.com
Organoids are 3D cell culture systems that mimic some of the structural and functional
characteristics of an organ. Organoid cultures provide the opportunity to study organ-level …

The 3D bioprinted scaffolds for wound healing

PE Antezana, S Municoy, MI Álvarez-Echazú… - Pharmaceutics, 2022 - mdpi.com
Skin tissue engineering and regeneration aim at repairing defective skin injuries and
progress in wound healing. Until now, even though several developments are made in this …

Hyaluronic acid‐based Bioconjugate systems, Scaffolds, and their therapeutic potential

NG Kotla, IL Mohd Isa, A Larrañaga… - Advanced …, 2023 - Wiley Online Library
In recent years, the development of hyaluronic acid or hyaluronan (HA) based scaffolds,
medical devices, bioconjugate systems have expanded into a broad range of research and …

Hyaluronic acid: A review of the drug delivery capabilities of this naturally occurring polysaccharide

C Buckley, EJ Murphy, TR Montgomery, I Major - Polymers, 2022 - mdpi.com
The inclusion of physiologically active molecules into a naturally occurring polymer matrix
can improve the degradation, absorption, and release profile of the drug, thus boosting the …

Dissecting and rebuilding the glioblastoma microenvironment with engineered materials

KJ Wolf, J Chen, JD Coombes, MK Aghi… - Nature Reviews …, 2019 - nature.com
Glioblastoma (GBM) is the most aggressive and common form of primary brain cancer.
Several decades of research have provided great insight into GBM progression; however …

Hyaluronic acid biomaterials for central nervous system regenerative medicine

G Jensen, JL Holloway, SE Stabenfeldt - Cells, 2020 - mdpi.com
Hyaluronic acid (HA) is a primary component of the brain extracellular matrix and functions
through cellular receptors to regulate cell behavior within the central nervous system (CNS) …

Preparation and evaluation of curcumin grafted hyaluronic acid modified pullulan polymers as a functional wound dressing material

Y Duan, K Li, H Wang, T Wu, Y Zhao, H Li, H Tang… - Carbohydrate …, 2020 - Elsevier
Curcumin grafted hyaluronic acid modified pullulan polymers (Cur-HA-SPu) by chemical
conjugation was designed and prepared, and its film may be used to accelerate wound …

[HTML][HTML] Mussel-inspired extracellular matrix-mimicking hydrogel scaffold with high cell affinity and immunomodulation ability for growth factor-free cartilage …

D Gan, Y Jiang, Y Hu, X Wang, Q Wang, K Wang… - Journal of orthopaedic …, 2022 - Elsevier
Background Injury to articular cartilage cause certain degree of disability due to poor self-
repair ability of cartilage tissue. To promote cartilage regeneration, it is essential to develop …