Cells respond to and actively remodel the extracellular matrix (ECM). The dynamic and
bidirectional interaction between cells and ECM, especially their mechanical interactions …

Tumor microenvironment is formed by various cellular and non-cellular components which
interact with one another and form a complex network of interactions. Some of these cellular …

Even though nanoparticle drug delivery systems (nanoDDSs) have improved antitumor
efficacy by delivering more drugs to tumor sites compared to free and unencapsulated …

Purpose Regular exercise can reduce incidence and progression of breast cancer, but the
mechanisms for such effects are not fully understood. The purpose of this study was to …

Proteoglycan macromolecules play key roles in several physiological processes (eg,
adhesion, proliferation, migration, invasion, angiogenesis, and apoptosis), all of which are …

Cervical cancer is associated with the highest morbidity rate among gynecological cancers.
Radiotherapy plays an important role in the treatment of cervical cancer. However, a …

Backgrounds Kidney renal clear cell carcinoma (KIRC) is a major pathological type of renal
cell carcinoma (RCC), and the prognosis of advanced KIRC patients is often unsatisfactory …

The development and progression of tumors in human tissues extensively rely on its
surrounding environment, that is, tumor microenvironment which includes a variety of cells …

In genome research, it is a fundamental issue to identify few but important survival‐related
biomarkers. The Cox model is a widely used survival analysis technique, which is used to …

Compelling pieces of evidence derived from both clinical and experimental research has
demonstrated the crucial contribution of diabetes mellitus (DM) as a risk factor associated …