Structure and biological activity of ergostane-type steroids from fungi

VN Zhabinskii, P Drasar, VA Khripach - Molecules, 2022 - mdpi.com
Mushrooms are known not only for their taste but also for beneficial effects on health
attributed to plethora of constituents. All mushrooms belong to the kingdom of fungi, which …

Paecilomyces cicadae: a systematic overview of the biological activities and potential mechanisms of its active metabolites

D Feiqian, Z Jiachan, C Wenjing, L Luyao… - Food and Agricultural …, 2023 - Taylor & Francis
ABSTRACT The microbe Paecilomyces cicadae (Miquel) Samson (P. cicadae) is an asexual
strain of Cordyceps cicadae (C. cicadae) used in traditional Chinese medicine. Due to the …

[HTML][HTML] Mitochondrial targeted modification and anticancer mechanism of natural product ergosterol peroxide

P Liu, Y Yang, Z Zhou, X Zhang, X Liu, J Li - Bioorganic Chemistry, 2024 - Elsevier
Ergosterol peroxide (EP) isolated from the edible medicinal fungus Pleurotus ferulae has a
wide range of anti-tumor activity, but poor water solubility and low bioavailability limit further …

Terpenoids and steroids from aerial parts of Achillea alpina L. as PTP1B inhibitors: Kinetic analysis and molecular docking studies

TT Le, MT Ha, GS Lee, VP Nguyen, CS Kim, JA Kim… - Phytochemistry, 2025 - Elsevier
Achillea alpina L.(Alpine yarrow) is a noteworthy herb in the genus Achillea with many uses
in vegetables and traditionally used to treat stomach disorders. In our continuous research …

Nephroprotective effects of two Ganoderma species methanolic extracts in an in vitro model of cisplatin induced tubulotoxicity

S Sinaeve, C Husson, MH Antoine, S Welti, C Stévigny… - Journal of Fungi, 2022 - mdpi.com
Although cisplatin is used as a first-line therapy in many cancers, its nephrotoxicity remains
a real problem. Acute kidney injuries induced by cisplatin can cause proximal tubular …

Chemical Diversity, Pharmacology, Synthesis and Detection of Naturally Occurring Peroxides

N Eka Ningrum… - Chemistry & …, 2024 - Wiley Online Library
Natural occurring peroxides are interesting bioprospecting targets due to their molecular
structural diversity and the wide range of pharmacological activities. In this systematic …

Antimicrobial Activities of Ganoderma mbrekobenum Strain EGDA (Agaricomycetes) from Egypt

MMN El-Dein, AA El-Fallal… - … Journal of Medicinal …, 2023 - dl.begellhouse.com
Ganoderma is a well-known genus of medicinal mushrooms. The biological activity of the
fruiting bodies of G. mbrekobenum (previously identified as Ganoderma sp. EGDA,(AC …

Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Polysaccharides Suppressed Adipogenesis and Stimulated Lipolysis in HPA-v and …

S Bu, H Zheng, C Yuan, Z Tian, C Xu… - … Journal of Medicinal …, 2020 - dl.begellhouse.com
Ganoderma lucidum polysaccharides (GLP) are one of the major bioactive components with
many beneficial properties. In the present study we aimed to systematically evaluate the …

Bioactive Compounds from Macrofungi and their Potential Applications

HM El-Gharabawy, MS Serag - Bioprospects of Macrofungi, 2023 - taylorfrancis.com
A solution for drug discovery and development may arise from the exploration of novel
bioactive compounds found in macrofungi. Because of their therapeutic and nutritional …

Exploring the Molecular Mechanisms of Huaier on Modulating Metabolic Reprogramming of Hepatocellular Carcinoma: A Study based on Network Pharmacology …

Y Wan, H Jiang, Z Liu, C Bai, Y Lian… - Current …, 2024 - vestnik.nvsu.ru
Background: Huaier (Trametes robiniophila Murr), a traditional Chinese medicine, is widely
used in China as a complementary and alternative therapy to treat hepatocellular carcinoma …