Milk microRNAs in health and disease

A Benmoussa, P Provost - … Reviews in food science and food …, 2019 - Wiley Online Library
MicroRNAs are small noncoding RNAs responsible for regulating 40% to 60% of gene
expression at the posttranscriptional level. The discovery of circulating microRNAs in several …

[HTML][HTML] Exosomes of pasteurized milk: potential pathogens of Western diseases

BC Melnik, G Schmitz - Journal of translational medicine, 2019 - Springer
Milk consumption is a hallmark of western diet. According to common believes, milk
consumption has beneficial effects for human health. Pasteurization of cow's milk protects …

Porcine milk exosome MiRNAs attenuate LPS-induced apoptosis through inhibiting TLR4/NF-κB and p53 pathways in intestinal epithelial cells

MY Xie, LJ Hou, JJ Sun, B Zeng, QY Xi… - Journal of agricultural …, 2019 - ACS Publications
Lipopolysaccharide (LPS) is a bacterial endotoxin that induces intestine inflammation. Milk
exosomes improve the intestine and immune system development of newborns. This study …

[HTML][HTML] Extracellular vesicles and asthma—More than just a co-existence

B Alashkar Alhamwe, DP Potaczek, S Miethe… - International journal of …, 2021 - mdpi.com
Extracellular vesicles (EVs) are membranous structures, which are secreted by almost every
cell type analyzed so far. In addition to their importance for cell-cell communication under …

[HTML][HTML] Extracellular vesicles from animal milk: great potentialities and critical issues

S Mecocci, M Trabalza-Marinucci, K Cappelli - Animals, 2022 - mdpi.com
Simple Summary Milk represents the main source of nutrition for newborn mammals and
serves as the conveyor of maternal messages of a sophisticated signaling system to …

Protective effects of bovine milk exosomes against oxidative stress in IEC-6 cells

L Wang, Z Shi, X Wang, S Mu, X Xu, L Shen… - European journal of …, 2021 - Springer
Purpose Bovine milk exosomes, which are enriched with microRNAs (miRNAs) and
proteins, regulate immune response and growth. In the present study, we aimed to assess …

[HTML][HTML] Concentrates of two subsets of extracellular vesicles from cow's milk modulate symptoms and inflammation in experimental colitis

A Benmoussa, I Diallo, M Salem, S Michel, C Gilbert… - Scientific reports, 2019 - nature.com
Extracellular vesicles (EVs) are involved in cell-to-cell communication and modulation of
numerous physiological and pathological processes. EVs are found in large quantities in …

[HTML][HTML] Mouse lung mechanical properties under varying inflation volumes and cycling frequencies

KAM Quiros, TM Nelson, S Sattari, CA Mariano, A Ulu… - Scientific reports, 2022 - nature.com
Respiratory pathologies alter the structure of the lung and impact its mechanics. Mice are
widely used in the study of lung pathologies, but there is a lack of fundamental mechanical …

Generation, purification and engineering of extracellular vesicles and their biomedical applications

J Gao, X Dong, Z Wang - Methods, 2020 - Elsevier
Extracellular vesicles (EVs), derived from cell membranes, demonstrate the potential to be
excellent therapeutics and drug carriers. Although EVs are promising, the process to …

[HTML][HTML] Dietary depletion of milk exosomes and their microRNA cargos elicits a depletion of miR-200a-3p and elevated intestinal inflammation and chemokine (CXC …

D Wu, H Kittana, J Shu, SD Kachman, J Cui… - Current Developments …, 2019 - Elsevier
Background Exosomes transfer regulatory microRNAs (miRs) from donor cells to recipient
cells. Exosomes and miRs originate from both endogenous synthesis and dietary sources …