Chronic nicotine exposure gives rise to neural adaptations that change whole cell
physiology and behaviour mainly by interacting with neuronal nicotinic acetylcholine …

The amino acid sequences of nicotinic acetylcholine receptors (nAChRs) from diverse
species can be compared across extracellular, transmembrane, and intracellular domains …

The number of nicotinic acetylcholine receptors (AChRs) present in the plasma membrane
of muscle and neuronal cells is limited by the assembly of individual subunits into mature …

Upregulation of neuronal nicotinic acetylcholine receptors (AChRs) is a venerable result of
chronic exposure to nicotine; but it is one of several consequences of pharmacological …

Upregulation of β2 subunit-containing (β2*) nicotinic acetylcholine receptors (nAChRs) is
implicated in several aspects of nicotine addiction, and menthol cigarette smokers tend to …

Secretory cargo is recognized, concentrated and trafficked from endoplasmic reticulum (ER)
exit sites (ERES) to the Golgi. Cargo export from the ER begins when a series of highly …

Nicotine dependence is thought to arise in part because nicotine permeates into the
endoplasmic reticulum (ER), where it binds to nicotinic receptors (nAChRs) and begins an …

Background Ethanol (EtOH) and nicotine are often co‐abused. However, their combined
effects on fetal neural development, particularly on fetal neural stem cells (NSC s), which …

Ca2+ is a major second messenger involved in cellular and subcellular signaling in a wide
range of cells, including astrocytes, which use calcium ions to communicate with other cells …

Glycosylphosphatidylinositol-anchored neurotoxin-like receptor binding proteins, such as
lynx modulators, are topologically positioned to exert pharmacological effects by binding to …