Articular cartilage serves as a low-friction, load-bearing tissue without the support with blood
vessels, lymphatics and nerves, making its repair a big challenge. Transforming growth …

Versatile strategies have been developed to construct electrospun fiber-based drug delivery
systems for tissue regeneration and cancer therapy. We first introduce the construction of …

The high density structure of cartilage matrix negative charge seriously hinders the
penetration and enrichment of drugs/genes into cartilage tissue. In this study …

The excessive reactive oxygen species (ROS) level, inflammation, and weak tissue
regeneration ability after annulus fibrosus (AF) injury constitute an unfavorable …

Tissue engineering and regenerative medicine have emerged as innovative approaches to
enhance clinical outcomes by addressing tissue lesions and degenerations that can …

Electrospinning is a simple, cost-effective, flexible, and feasible continuous micro-nano
polymer fiber preparation technology that has attracted extensive scientific and industrial …

Articular cartilage injury is a frequent worldwide disease, while effective treatment is urgently
needed. Due to lack of blood vessels and nerves, the ability of cartilage to self-repair is …

Oxidative stress is a biochemical process that disrupts the redox balance due to an excess
of oxidized substances within the cell. Oxidative stress is closely associated with a multitude …

Hyaluronic acid (HA), an anionic and nonsulfated glycosaminoglycan, is the main structural
component of various tissues and plays an important role in various biological processes …

The rapid development of tissue engineering makes it an effective strategy for repairing
cartilage defects. The significant advantages of injectable hydrogels for cartilage injury …