Betulinic and ursolic acids from Nauclea latifolia roots mediate their antimalarial activities through docking with PfEMP-1 and PfPKG proteins
Abstract Background Chemotherapies target the PfEMP-1 and PfPKG proteins in
Plasmodium falciparum, the parasite that causes malaria, in an effort to prevent the …
Plasmodium falciparum, the parasite that causes malaria, in an effort to prevent the …
Fatty Acid Esters and Acyclic Monoterpenoid from Justicia insularis Leaf Fractions Attenuated Malaria Pathogenesis Through Docking with Plasmodium falciparum …
Background Justicia insularis (Acanthaceae) T. Anderson is ethnopharmacologically used in
Nigeria for the treatment of diseases including malaria. Therefore, this study was designed …
Nigeria for the treatment of diseases including malaria. Therefore, this study was designed …
Antimalarial activity of Mangifera indica aqueous extract in Plasmodium berghei's apicoplast
Purpose: To investigate the in vivo antiplasmodial effect of Mangifera indica aqueous extract
in Plasmodium berghei-infected mice, and to characterize its phytochemical constituents …
in Plasmodium berghei-infected mice, and to characterize its phytochemical constituents …
Antiplasmodial Profiling of Mangifera indica's Herbal Formulation and Its Ability to Ameliorate Hematological Derangements in Plasmodium berghei-Infected Mice
Background Malaria caused by Plasmodium falciparum with an average prevalence of 75%
in Nigeria, can be treated. Chemical-based medications, one of the methods used to treat it …
in Nigeria, can be treated. Chemical-based medications, one of the methods used to treat it …
New Perspectives on the Therapeutic Potentials of Bioactive Compounds from Curcuma longa: Targeting COX-1 & 2, PDE-4B, and Antioxidant Enzymes to …
Background Inflammations, oxidative stress, and pains underlie the pathogenesis of non-
communicable diseases (NCDs) like respiratory disorders and cancer; however, they are …
communicable diseases (NCDs) like respiratory disorders and cancer; however, they are …
Unravelling therapeutic potentials of Solanum anomalum fruits: antiplasmodial, hepatoprotective, and anti-oxidative stress activities, semi-purification, GC-MS, and in …
Background The high prevalence rate of malaria due to the proliferation of drug-resistant
strains of Plasmodium falciparum could mitigate the realization of sustainable development …
strains of Plasmodium falciparum could mitigate the realization of sustainable development …
Isolation of a Lauryl Alcohol (1-Dodecanol) from the Antioxidant Bioactive Fractions of Justicia insularis (Acanthaceae) Leaves
Background Scientific and ethnopharmacological studies have shown that Justicia insularis
leaves are used in the treatment of oxidative stress, heart problems, labour pains, and …
leaves are used in the treatment of oxidative stress, heart problems, labour pains, and …
The antimalarial profiling of Mangifera indica's herbal formulation attenuated biochemical alterations and improved hepatocytes' histoarchitecture in Plasmodium …
Plasmodium parasite causes malaria and affects the biochemical, physiological, and
histoarchitecture of the hepatocytes and blood. The resultant effect leads to alterations in the …
histoarchitecture of the hepatocytes and blood. The resultant effect leads to alterations in the …
Abietic acid ameliorates pancreatic injury in acute pancreatitis by modulating MAPK pathway
H Ye, J Wang, J Mao, D Pan - Tropical Journal of Pharmaceutical Research, 2023 - ajol.info
Purpose: To examine the effect of abietic acid (AA) in the treatment of acute pancreatitis (AP)
in mice. Methods: C57BL/6J mice were randomly assigned to 4 groups: sham, AP, AP+ 20 …
in mice. Methods: C57BL/6J mice were randomly assigned to 4 groups: sham, AP, AP+ 20 …