[HTML][HTML] Heat Shock Factor 1 Inhibition: A Novel Anti-Cancer Strategy with Promise for Precision Oncology

KE Gumilar, Y Chin, IH Ibrahim, BA Tjokroprawiro… - Cancers, 2023 - mdpi.com
Simple Summary Heat shock factor 1 (HSF1) is a transcription factor crucial for cellular
stress responses. HSF1 activates heat shock proteins (HSPs) in response to proteotoxic …

[HTML][HTML] Detection of driver mutations and genomic signatures in endometrial cancers using artificial intelligence algorithms

A Stan, K Bosart, M Kaur, M Vo, W Escorcia, RJ Yoder… - Plos one, 2024 - journals.plos.org
Analyzed endometrial cancer (EC) genomes have allowed for the identification of molecular
signatures, which enable the classification, and sometimes prognostication, of these …

[PDF][PDF] Tamoxifen Alleviates Endometrial Fibrosis Induced by Anhydrous Ethanol in Rats

H Jiang, J Song, M Yang, X He, H Wang… - Discovery …, 2024 - scholar.archive.org
Background: As an estrogen receptor modulator, tamoxifen has been utilized in the
treatment of fibrotic diseases. However, there is a limited body of research focusing on its …

Antitumor Activity of Antiestrogen-Cytostatics and Their Binding Affinity with Estrogen Receptors

AR Dublin, AV Semeikin, TA Fedotcheva… - Pharmaceutical …, 2024 - Springer
Compounds Ro-714, Ro-716, and Ro-728 containing an antiestrogenic steroid moiety
associated with a bis-β-chloroethylamine group exhibit pronounced antitumor activity in …

[HTML][HTML] 中药单体在子宫内膜癌中抗肿瘤机制的研究进展

王甜慧, 赵子雪, 樊婷婷 - Advances in Clinical Medicine, 2023 - hanspub.org
子宫内膜癌凭借复杂的发病机制及不良的预后特征, 成为严重危害女性身心健康的恶性肿瘤.
随着科技的进步, 针对子宫内膜癌的诊疗计划也在不断地被深入研讨, 其中, 中药单体在治疗角度 …

HSF1 Inhibition: A Novel Anti-Cancer Strategy with Promise for Precision Oncology

KE Gumilar, Y Chin, IH Ibrahim, BA Tjokroprawiro… - 2023 - preprints.org
Abstract Heat shock factor 1 (HSF1) is a transcription factor crucial for regulating heat shock
response (HSR), one of the significant cellular protective mechanisms. When cells are …

Морфогенетичні особливості гіперпластичних процесів ендометрія

НЛ Циндренко - 2024 - essuir.sumdu.edu.ua
Актуальність дослідження гіперпластичних процесів ендометрія (ГПЕ) обумовлена
значною поширеністю цієї патології у жінок різного віку, високим потенціалом до …