Developmental origins of disease-crisis precipitates change

C Reichetzeder, SE Dwi Putra, J Li… - Cellular Physiology and …, 2016 - karger.com
The concept of developmental origins of diseases has gained a huge interest in recent years
and is a constantly emerging scientific field. First observations hereof originated from …

[HTML][HTML] Genetic evidence for causal relationships between maternal obesity-related traits and birth weight

J Tyrrell, RC Richmond, TM Palmer, B Feenstra… - Jama, 2016 - jamanetwork.com
Importance Neonates born to overweight or obese women are larger and at higher risk of
birth complications. Many maternal obesity-related traits are observationally associated with …

Parental genetic effects on the offspring's phenotype without transmission of the gene itself—pathophysiology and clinical evidence

X Zhang, B Hocher - American Journal of Physiology-Cell …, 2024 - journals.physiology.org
Parental genes can influence the phenotype of their offspring through genomic-epigenomic
interactions even without the direct inheritance of specific parental genotypes. Maternal …

Fetal sex and maternal risk of gestational diabetes mellitus: the impact of having a boy

R Retnakaran, CK Kramer, C Ye, S Kew… - Diabetes …, 2015 - Am Diabetes Assoc
OBJECTIVE Retrospective analyses of perinatal databases have raised the intriguing
possibility of an increased risk of gestational diabetes mellitus (GDM) in women carrying a …

A novel common variant in DCST2 is associated with length in early life and height in adulthood

RJP van der Valk, E Kreiner-Møller… - Human molecular …, 2015 - academic.oup.com
Common genetic variants have been identified for adult height, but not much is known about
the genetics of skeletal growth in early life. To identify common genetic variants that …

Loss of insulin-induced activation of TRPM6 magnesium channels results in impaired glucose tolerance during pregnancy

AV Nair, B Hocher, S Verkaart… - Proceedings of the …, 2012 - National Acad Sciences
Hypomagnesemia affects insulin resistance and is a risk factor for diabetes mellitus type 2
(DM2) and gestational diabetes mellitus (GDM). Two single nucleotide polymorphisms …

Fetal sex is associated with maternal stimulated cytokine production, but not serum cytokine levels, in human pregnancy

AM Mitchell, M Palettas, LM Christian - Brain, behavior, and immunity, 2017 - Elsevier
Some studies suggest that fetal sex plays a role in maternal physiological processes during
pregnancy including glycemic control, blood pressure, and cortisol regulation. However …

[HTML][HTML] Magnesium enhances exercise performance via increasing glucose availability in the blood, muscle, and brain during exercise

HY Chen, FC Cheng, HC Pan, JC Hsu, MF Wang - Plos one, 2014 - journals.plos.org
Glucose mobilization and utilization in the periphery and central nervous system are
important during exercise and are responsible for exercise efficacy. Magnesium (Mg) is …

Sexually dimorphic adaptations in basal maternal stress physiology during pregnancy and implications for fetal development

GF Giesbrecht, T Campbell, N Letourneau… - …, 2015 - Elsevier
There is clear evidence of reciprocal exchange of information between the mother and fetus
during pregnancy but the majority of research in this area has focussed on the fetus as a …

Plasma ET-1 concentrations are elevated in pregnant women with hypertension-meta-analysis of clinical studies

YP Lu, AA Hasan, S Zeng, B Hocher - Kidney and Blood Pressure …, 2017 - karger.com
Abstract Background/Aims: The ET system might be involved in the pathogenesis of
hypertensive disorders during pregnancy. The objective is to analyse the impact of ET-1 in …