TP53 mutations and hepatocellular carcinoma: insights into the etiology and pathogenesis of liver cancer
Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide and
the major risk factors include chronic infections with the hepatitis B (HBV) or C (HCV) virus …
the major risk factors include chronic infections with the hepatitis B (HBV) or C (HCV) virus …
Cyclo-oxygenase 2: a pharmacological target for the prevention of cancer
AJ Dannenberg, NK Altorki, JO Boyle, C Dang… - The lancet …, 2001 - thelancet.com
Understanding the mechanisms underlying carcinogenesis provides insights that are
necessary for the development of therapeutic strategies to prevent cancer …
necessary for the development of therapeutic strategies to prevent cancer …
Cyclooxygenase-2 and epidermal growth factor receptor: pharmacologic targets for chemoprevention
AJ Dannenberg, SM Lippman, JR Mann… - Journal of clinical …, 2005 - ascopubs.org
Understanding the mechanisms underlying carcinogenesis provides insights that are
necessary for the development of therapeutic strategies to prevent cancer …
necessary for the development of therapeutic strategies to prevent cancer …
[HTML][HTML] The prognostic molecular markers in hepatocellular carcinoma
LX Qin, ZY Tang - World journal of gastroenterology, 2002 - ncbi.nlm.nih.gov
The prognosis of hepatocellular carcinoma (HCC) still remains dismal, although many
advances in its clinical study have been made. It is important for tumor control to identify the …
advances in its clinical study have been made. It is important for tumor control to identify the …
Cyclooxygenase–2 Promotes Hepatocellular Carcinoma Cell Growth Through Akt Activation: Evidence for Akt Inhibition in Celecoxib–Induced Apoptosis
J Leng, C Han, JA Demetris, GK Michalopoulos… - Hepatology, 2003 - journals.lww.com
Abstract Cyclooxygenase–2 (COX–2)–controlled prostaglandin (PG) metabolism recently
has been implicated in the pathogenesis of hepatocellular carcinoma (HCC). However, the …
has been implicated in the pathogenesis of hepatocellular carcinoma (HCC). However, the …
Cyclooxygenase-2 expression in human gliomas: prognostic significance and molecular correlations
T Shono, PJ Tofilon, JM Bruner, O Owolabi, FF Lang - Cancer research, 2001 - AACR
Abstract Cyclooxygenase (COX)-2, the inducible isoform of prostaglandin H synthase, has
been implicated in the growth and progression of a variety of human cancers. Although COX …
been implicated in the growth and progression of a variety of human cancers. Although COX …
Coexpression of inducible nitric oxide synthase and COX-2 in hepatocellular carcinoma and surrounding liver: possible involvement of COX-2 in the angiogenesis of …
MA Rahman, DK Dhar, E Yamaguchi, S Maruyama… - Clinical Cancer …, 2001 - AACR
Expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) has
been reported to be responsible for enhanced tumor growth and angiogenesis in various …
been reported to be responsible for enhanced tumor growth and angiogenesis in various …
Omega-3 polyunsaturated fatty acids inhibit hepatocellular carcinoma cell growth through blocking β-catenin and cyclooxygenase-2
Hepatocellular carcinoma (HCC) is a common human cancer with high mortality, and
currently, there is no effective chemoprevention or systematic treatment. Recent evidence …
currently, there is no effective chemoprevention or systematic treatment. Recent evidence …
[HTML][HTML] Omega-3 fatty acids to augment cancer therapy
WE Hardman - The Journal of nutrition, 2002 - Elsevier
The results of animal studies have demonstrated that the consumption of omega-3 fatty
acids can slow the growth of cancer xenografts, increase the efficacy of chemotherapy and …
acids can slow the growth of cancer xenografts, increase the efficacy of chemotherapy and …
Expression of cyclooxygenase-2 (COX-2) in hepatocellular carcinoma and growth inhibition of hepatoma cell lines by a COX-2 inhibitor, NS-398
SH Bae, ES Jung, YM Park, BS Kim, BK Kim… - Clinical Cancer …, 2001 - AACR
Abstract Cyclooxygenase-2 (COX-2) has been suggested to be associated with
carcinogenesis. In hepatocellular carcinoma (HCC), the expression pattern of COX-2 protein …
carcinogenesis. In hepatocellular carcinoma (HCC), the expression pattern of COX-2 protein …