Ocular surface toxicities associated with modern anticancer therapies

R Boucher, O Haigh, E Barreau, S Champiat… - Survey of …, 2024 - Elsevier
Cancer treatments have recently shifted from broad-spectrum cytotoxic therapies to more
focused treatments, maximizing anticancerous activity while reducing toxicity to healthy …

Ocular toxicity of targeted anticancer agents

BH Fortes, PD Tailor, LA Dalvin - Drugs, 2021 - Springer
The proliferation of targeted anticancer agents over the last two decades has revolutionized
cancer treatment and improved survival in many previously refractory malignancies …

[PDF][PDF] Sicca/Sjögren's syndrome triggered by PD-1/PD-L1 checkpoint inhibitors. Data from the International ImmunoCancer Registry (ICIR)

M Ramos-Casals, A Maria… - Clin Exp …, 2019 - clinexprheumatol.org
Objective. To analyse the worldwide occurrence of sicca/Sjögren's (SS) syndrome
associated with the use of immune checkpoint inhibitors (ICI) in patients with cancer …

Epidermal growth factor receptor expression in the corneal epithelium

JL Peterson, BP Ceresa - Cells, 2021 - mdpi.com
A properly functioning cornea is critical to clear vision and healthy eyes. As the most anterior
portion of the eye, it plays an essential role in refracting light onto the retina and as an …

[HTML][HTML] CAR-T cell therapy in ovarian cancer: from the bench to the bedside

X Zhu, H Cai, L Zhao, L Ning, J Lang - Oncotarget, 2017 - ncbi.nlm.nih.gov
Ovarian cancer (OC) is the most lethal gynecological malignancy and is responsible for most
gynecological cancer deaths. Apart from conventional surgery, chemotherapy, and …

Retinal toxicities of systemic anticancer drugs

S Arora, T Surakiatchanukul, T Arora, MH Errera… - Survey of …, 2022 - Elsevier
Newer anticancer drugs have revolutionized cancer treatment in the last decade, but
conventional chemotherapy still occupies a central position in many cancers, with …

Antibody-drug conjugates and ocular toxicity

M Jaffry, H Choudhry, OM Aftab… - Journal of Ocular …, 2023 - liebertpub.com
Antibody-drug conjugates (ADCs) are a growing class of chemotherapeutic agents for the
purpose of treating cancers that often have relapsed or failed first-and second-line …

Corneal features in trastuzumab emtansine treatment: not a rare occurrence

E Deklerck, H Denys, EO Kreps - Breast Cancer Research and Treatment, 2019 - Springer
Purpose Ado-trastuzumab emtansine (T-DM1/Kadcyla®; Genentech) is an antibody-drug
conjugate used in the treatment of human epidermal growth factor receptor-2-positive …

Ocular Surface Side Effects of Novel Anticancer Drugs

L Vitiello, F Lixi, G Coco, G Giannaccare - Cancers, 2024 - mdpi.com
Simple Summary Anticancer drugs can determine alterations in the ocular surface system as
side effects that can be referred to by patients as ocular discomfort symptoms and …

Abnormal corneal lesions induced by trastuzumab emtansine: an antibody–drug conjugate for breast cancer

M Tsuda, Y Takano, C Shigeyasu, S Imoto, M Yamada - Cornea, 2016 - journals.lww.com
Purpose: To report a case of atypical corneal lesions presumably induced by trastuzumab
emtansine, an antibody–drug conjugate that is designed to selectively deliver cytotoxic …