In hibitor of G rowth 1 (ING1) was identified and characterized as a “candidate” tumor
suppressor gene in 1996. Subsequently, four more genes, also characterized as “candidate” …

Simple Summary The INhibitor of Growth (ING) family of proteins was founded when in 1996
ING1 was identified as a tumour suppressor, a protein that prevents cancer development …

Sin3/HDAC complexes function by deacetylating histones, condensing chromatin, and
modulating gene expression. Although components used to build these complexes have …

Flowering of the reference legume Medicago truncatula is promoted by winter cold
(vernalization) followed by long‐day photoperiods (VLD) similar to winter annual …

Abstract The INhibitor of Growth (ING) family of tumor suppressors regulates the
transcriptional state of chromatin by recruiting remodeling complexes to sites with histone …

Inhibitor of growth 4 and 5 (ING4, ING5) are structurally similar chromatin-binding proteins in
the KAT6A, KAT6B and KAT7 histone acetyltransferase protein complexes. Heterozygous …

The ING family of tumor suppressor genes is composed of five members (ING1-5) involved
in cell cycle regulation, DNA damage response, apoptosis and senescence. All ING proteins …

Summary Collagen prolyl 4-hydroxylase (C-P4H) catalyzes the proline hydroxylation of
procollagen, an essential modification in the maturation of collagens. C-P4H consists of two …

Colorectal cancer (CRC) is the third most common malignant disease globally and causes
numerous cancer‑associated mortalities; however, the underlying molecular mechanisms …

Abstract Inhibitor of growth 4 (ING4), a member of the ING family discovered in 2003, has
been shown to act as a tumor suppressor and is frequently down-regulated in various …